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Characterization of CSOC 882, a novel immortalized ovarian cancer cell line exp…

Scoles(Daniel R),Pavelka(James),Cass(Ilana),… Gynecol Oncol 2007-02-15

...BRCA1, EGF receptor, HER2, androgen receptor, estrogen receptor alpha, and progesterone receptor, while no evidence of e...

The functional genetic variant Ile646Val located in the kinase binding domain o…

Wirtenberger(Michael),Schmutzhard(Julia),Hem… Carcinogenesis 2007-03-26

...BRCA1/2 mutation-negative familial breast cancer patients and 993 controls revealed an association of the AKAP10 Ile646V...

Heterozygote BRCA1 status and skewed chromosome X inactivation.

Helbling-Leclere(Anne),Lenoir(Gilbert M),Feu… Fam Cancer 2007-09-13

...BRCA1 mutation carrier women lack the hallmarks of inactive X chromatin structure. These observations suggested that los...

Occurrence of both breast and ovarian cancer in a woman is a marker for the BRC…

Einbeigi(Zakaria),Bergman(Annika),Meis-Kindb… Fam Cancer 2007-09-13

...BRCA1 c.3171_3175dup (c.3171ins5), which is most common in this geographic area and four other common Scandinavian BRCA1...

The 471delAAAG mutation and C353T polymorphism in the RNASEL gene in sporadic a…

Dagan(Efrat),Laitman(Yael),Levanon(Nurit),Fe… Fam Cancer 2007-09-20

...BRCA1/2 mutation carriers, 205 high-risk non-carriers matched for cancer type and age at diagnosis, and 192 healthy Ashk...

The asynaptic chromatin in spermatocytes of translocation carriers contains the…

Sciurano(R),Rahn(M),Rey-Valzacchi(G),Solari(… Hum Reprod 2007-03-16

...BRCA1 located on the axes and the variant histone gamma-H2AX located on the chromatin. The area covered by gamma-H2AX in...

Human immunodeficiency virus type 1 Vpr induces G2 checkpoint activation by int…

Terada(Yasuhiko),Yasuda(Yuko) Mol Cell Biol 2007-01-30

...BRCA1) nuclear foci, and a C-terminal domain is required for Vpr-induced ATR activation and its nuclear localization. Ho...

PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA…

De Soto(Joseph A),Deng(Chu-Xia) Int J Med Sci 2007-06-18

...BRCA1 status in allograft nude mice. Non-specific inhibition in human BRCA1+/+, BRCA1+/-, and BRCA1-/- breast cancer cel...

Evaluation of BRCA1 and BRCA2 mutation prevalence, risk prediction models and a…

Simard(Jacques),Dumont(Martine),Moisan(Anne-… J Med Genet 2007-06-07

...BRCA1 or BRCA2 in a large series of families with breast cancer in the French-Canadian population of Quebec, Canada are ...

BRCA1--a good predictive marker of drug sensitivity in breast cancer treatment?

Mullan(Paul B),Gorski(Julia J),Harkin(D Paul) Biochim Biophys Acta 2007-02-01

...BRCA1 is an important genetic factor in hereditary breast and ovarian cancer and there is increasing evidence of an impo...

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