...BRCA1 are predisposed to develop breast and ovarian cancers. A previous report indicated that BRCA1 colocalizes with and...
BRCA1, a breast and ovarian cancer-suppressor gene, exerts tumor-suppressing functions that appear to be associated, at ...
...BRCA1 and the subsequent formation of the Rad51 nucleoprotein filament at DSBs are abolished in Ubc13-deficient cells. F...
...Brca1 and Parp1, we interbred mice carrying a heterozygous deletion of full-length Brca1 (Brca1(+/Delta11)) with Parp1-n...
...BRCA1-associated breast cancers, which suggests that dysfunction in BRCA1 or related pathways occurs in this subset of s...
...BRCA1/2 mutations a one-year series of patients (34 females, 1 male) selected by diagnosis within age 40 years or male g...
...BRCA1/2-mutations, p(mut), and p(life). In this study, the models are compared with Ford and Claus penetrance/frequency ...
...BRCA1. Taken together, these findings reveal that hypoxia induces a unique cellular stress response involving an initial...
...BRCA1 and BRCA2 carriers are unknown.,We assessed breast cancer risk in a large series of 1,187 BRCA1 and 414 BRCA2 carr...
Genetic counseling is now routinely offered to individuals at high risk of carrying a BRCA1 or BRCA2 mutation. Risk pred...
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