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TP53 BRCA1 CRISPR single-cell cancer

Jeng(Y-M),Cai-Ng(S),Li(A),Furuta(S),Chew(H),… Oncogene 2007-10-24

BRCA1 mutation carriers have an 85% lifetime risk of breast cancer and 60% for ovarian cancer. BRCA1 facilitates DNA dou...

Tischkowitz(Marc),Xia(Bing),Sabbaghian(Nelly… Proc Natl Acad Sci U S A 2007-06-06

...BRCA1, BRCA2, TP53, CHEK2, ATM, and FANCJ/BRIP1, function in DNA repair, raising the possibility that germ line mutation...

Horwitz(Andrew A),Affar(El Bachir),Heine(Geo… Proc Natl Acad Sci U S A 2007-06-06

...BRCA1 protein, we assessed the level of repression dependent on BRCA1 in the cell, and we found that BRCA1 is at least a...

Going(J J),Nixon(C),Dornan(E S),Boner(W),Don… Histopathology 2007-05-24

...BRCA1) and has homology with BRCA1 over the carboxyl terminal half of the protein. The aim of this study was to determin...

Rakha(E A),El-Sayed(M E),Green(A R),Paish(E … Histopathology 2007-05-24

...BRCA1, P-cadherin and myoepithelial markers (smooth muscle actin and p63) were studied in a well-characterized series of...

De Brakeleer(Sylvia),Bogdani(Marika),De Grèv… Mutat Res 2007-06-21

...BRCA1/2 mutation carriers, sporadic breast cancer patients and controls were prepared for BRCA1 immunocytochemistry. We ...

Broeks(Annegien),Braaf(Linde M),Huseinovic(A… Breast Cancer Res 2007-06-13

...BRCA1, BRCA2, CHEK2 and ATM to the risk of radiation-induced contralateral breast cancer (CBC). The germline mutation fr...

Baynes(Caroline),Healey(Catherine S),Pooley(… Breast Cancer Res 2007-06-13

Certain rare, familial mutations in the ATM, BRCA1, BRCA2, CHEK2 or TP53 genes increase susceptibility to breast cancer ...

Hinton(Cimona V),Fitzgerald(Latricia D),Thom… Exp Cell Res 2007-06-26

...BRCA1 is required for the heregulin-regulated nuclear concentration of BRCA1. Because most functions ascribed to BRCA1 o...

Geoffroy-Siraudin(C),Aknin-Seiffer(I),Metzle… Hum Reprod 2007-08-03

...BRCA1 and gammaH2AX. We quantified the leptotene, zygotene and pachytene stages, and pachytene abnormalities: asynapsis ...

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