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Contribution of BRCA1 and BRCA2 germline mutations to the incidence of early-on…

Loizidou(M),Marcou(Y),Anastasiadou(V),Newbol… Clin Genet 2007-04-11

...BRCA1 and BRCA2 genes were sequenced using cycle sequencing. We identified four pathogenic mutations: two in BRCA1 [c.18...

Timing of dietary estrogenic exposures and breast cancer risk.

De Assis(Sonia),Hilakivi-Clarke(Leena) Ann N Y Acad Sci 2007-03-13

...BRCA1, p53, and caveolin-1 are among the genes affected by diet-induced alterations in programming/reprogramming. Conseq...

Antihormones in prevention and treatment of breast cancer.

Ponzone(Riccardo),Biglia(Nicoletta),Jacomuzz… Ann N Y Acad Sci 2007-03-13

...BRCA1/2 mutation, this option cannot be advocated for the majority of women whose risk is only moderately increased. In ...

Hypermethylation of tumor suppressor genes BRCA1, p16 and 14-3-3sigma in serum …

Jing(Feng),Zhang(Jicai),Tao(Jianshu),Zhou(Yo… Onkologie 2007-03-20

We investigated the hypermethylation status in serum of sporadic breast cancer patients.,The hypermethylation status of ...

Camptothecin acts synergistically with imatinib and overcomes imatinib resistan…

Ju(Dong-Sik),Kim(Mi-Ju),Bae(Jae-Ho),Song(Hye… Cancer Lett 2007-08-16

...BRCA1, suggesting that loss of Bcr-Abl after exposure to imatinib might be accompanied by other cell survival mechanism....

A survey of preventive measures among BRCA1 mutation carriers from Poland.

Gronwald(J),Byrski(T),Huzarski(T),Cybulski(C… Clin Genet 2007-04-11

Among women with a BRCA1 mutation, the lifetime risks of breast and ovarian cancer are elevated. Several measures for re...

Functional characterization of a novel BRCA1-null ovarian cancer cell line in r…

DelloRusso(Christiana),Welcsh(Piri L),Wang(W… Mol Cancer Res 2007-03-01

...BRCA1 plays a major role in the DNA damage response pathway. The lack of well-characterized human BRCA1-null cell lines ...

MRI in the early detection of breast cancer in women with high genetic risk.

Trecate(Giovanna),Vergnaghi(Daniele),Manouki… Tumori 2007-02-20

Women with BRCA1 or BRCA2 germline mutations have an elevated risk of developing breast and/or ovarian cancer. Because o...

Reduced mammographic density with use of a gonadotropin-releasing hormone agoni…

Weitzel(Jeffrey N),Buys(Saundra S),Sherman(W… Clin Cancer Res 2007-04-24

...BRCA1 mutation (BRCA1(mut)) need risk reduction options beyond mastectomy and oophorectomy. We evaluated the efficacy, s...

Comparison of age distribution patterns for different histopathologic types of …

Anderson(William F),Pfeiffer(Ruth M),Dores(G… Cancer Epidemiol Biomarkers P… 2007-06-20

...BRCA1 gene. These descriptive and model-based results support emerging molecular data, suggesting two main types of brea...

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