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A multicenter study of cancer incidence in CHEK2 1100delC mutation carriers.

Thompson(Deborah),Seal(Sheila),Schutte(Mieke… Cancer Epidemiol Biomarkers P… 2007-04-09

...BRCA1/2 breast cancer families from the United Kingdom, Germany, Netherlands, and the United States was compared with th...

"Similarity trap" in protein-protein interactions could be carcinogenic: simula…

Liu(Jin),Pan(Yongping),Ma(Buyong),Nussinov(R… Structure 2007-02-01

...BRCA1-p53 interaction is weak or other mechanisms operate. To delineate the difference, we designed 13 BRCA1-BRCT mutant...

Phospho-dependent protein recognition motifs contained in C/EBP family of trans…

Miller(Maria) Cell Cycle 2007-07-11

...BRCA1). Proteins containing BRCT domains serve as scaffolds, mediating protein-protein interactions and formation of fun...

A gift or a yoke? Women's and men's responses to genetic risk information from …

d'Agincourt-Canning(L) Clin Genet 2007-01-24

This qualitative study explored the impact of genetic risk information from BRCA1/2 testing on individuals' subjective u...

Mutation analysis of BRCA1 and BRCA2 from 793 Korean patients with sporadic bre…

Han(S-H),Lee(K-R),Lee(D-G),Kim(B-Y),Lee(K-E)… Clin Genet 2007-01-24

To investigate the role of BRCA1 and BRCA2 mutations in Korean patients with sporadic breast cancer, 793 breast cancer p...

A discrete choice experiment of preferences for genetic counselling among Jewis…

Peacock(S),Apicella(C),Andrews(L),Tucker(K),… Br J Cancer 2007-01-16

...BRCA1 and BRCA2, and were offered their genetic test result through a cancer genetics service. Main outcome measures wer...

A novel BRCA1 mutation in an Indian family with hereditary breast/ovarian cance…

Gajalakshmi(P),Natarajan(Thanemozhi G),Selvi… Breast Cancer Res Treat 2007-06-26

Germ-line mutations in BRCA1 gene contribute to a majority of familial breast and ovarian cancers. A group of 23 Tamil N...

Effect of mammography on breast cancer risk in women with mutations in BRCA1 or…

Goldfrank(Deborah),Chuai(Shannon),Bernstein(… Cancer Epidemiol Biomarkers P… 2007-06-12

Women who carry mutations in either the BRCA1 or BRCA2 genes are at risk for early-onset breast cancer and are recommend...

Breast cancer risk associated with AURKA 91T -->A polymorphism in relation to B…

Vidarsdottir(Linda),Bodvarsdottir(Sigridur K… Cancer Lett 2007-06-25

...BRCA1 and 98 BRCA2 mutation carriers, and 653 mutation-negative unaffected controls were genotyped for the AURKA 91T -->...

Locoregional relapse and distant metastasis in conservatively managed triple ne…

Haffty(Bruce G),Yang(Qifeng),Reiss(Michael),… J Clin Oncol 2007-01-08

...BRCA1, and seven had mutations in BRCA2. Of 10 BRCA1 patients, eight were triple negative, whereas only one of seven BRC...

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