...BRCA1 tumors. A high LOH frequency was found in BRCA1 tumors (range 19-82%), as compared to BRCA2 and sporadic tumors (r...
...BRCA1/2 mutation had been proposed. The control group was surveyed before the booklet became available (n = 263), and th...
...BRCA1 and BRCA2 have been predominantly associated with the breast and ovarian cancers. Two mutations in BRCA1 (185delAG...
...BRCA1 or BRCA2 mutation. Evidence for linkage was assessed using parametric linkage analysis, assuming both a dominant a...
...BRCA1.,Genomic DNA was obtained for 102 healthy controls and 116 patients with established pathogenic mutations of BRCA1...
BRCA1 and BRCA2 mutation carriers are at increased risk for developing both breast and ovarian cancer. It has been sugge...
...Brca1, Xrcc1, and 53BP1. In Saccharomyces cerevisiae, Esc4 contains six such BRCT domains and is required for the most e...
...BRCA1, BRCA2, and p16. Elucidation of the origin of the hotspots in these genes requires more data on somatic mutations ...
...BRCA1 and BRCA2 were screened by multiple DNA-based and RNA-based methods to detect genomic rearrangements in BRCA1 and ...
Previously, we have reported that BRCA1 regulates the expression of various classes of genes, including genes involved i...
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