...BRCA1 and BRCA2. Despite the increasing demand for genetic testing arising from the patients and their relatives, the ge...
...BRCA1/2 mutation-negative index patients of 592 German BC families and 735 control individuals.,The T allele of rs122553...
...BRCA1 was positionally cloned in 1994. During the last 12 years, several lines of evidence have implicated BRCA1 in the ...
...BRCA1 and BRCA2. Correct staging of breast cancer patients is critical. It permits an accurate diagnosis, as well as in ...
Women who have germline mutations in the BRCA1 gene are at substantially increased lifetime risk of developing breast an...
...BRCA1 are predisposed to breast and ovarian cancers. Why the BRCA1 protein suppresses tumor development specifically in ...
...BRCA1, BRCA2, CHEK2 (RAD53), CYP17, CYP1B1, CYP3A4, GSTM1, GSTP1, GSTT1, PON1, SRD5A2, and VDR that have germline geneti...
...BRCA1 associated protein-1 [ubiquitin carboxy-terminal hydrolase (bap1)]; cell division cycle 2, G1 to S and G2 to M [cd...
Ovarian carcinomas from 30 BRCA1 germ-line carriers of two distinct high penetrant founder mutations, 20 carrying the 16...
It has been estimated that the lifetime risk of breast cancer among women who inherit a BRCA1 or BRCA2 mutation is as hi...
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