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TP53 BRCA1 CRISPR single-cell cancer

Hamann(Heidi A),Somers(Tamara J),Smith(Ashle… Psychosom Med 2006-07-18

...BRCA1/2 testing.,Participants were 84 women enrolled in a larger project focused on genetic testing decisions. Semistruc...

Ma(Hongxia),Hu(Zhibin),Zhai(Xiangjun),Wang(S… Carcinogenesis 2006-05-03

...BRCA1, we hypothesized that genetic variation in P53BP1 and p53 may contribute to breast cancer predisposition. To test ...

Larson(Pamela S),Schlechter(Benjamin L),de l… J Clin Oncol 2006-02-13

...BRCA1 gene mutation carriers (BRCA1; n = 16), and controls undergoing reduction mammoplasty (RM; n = 18). We analyzed th...

Kramer(Joan L),Velazquez(Isela A),Chen(Bings… J Clin Oncol 2006-02-13

Breast cancer penetrance estimates in BRCA1 mutation carriers have varied from 40% to 85%; this heterogeneity has been a...

Tilanus-Linthorst(Madeleine M A),Bartels(Kar… Breast Cancer Res Treat 2006-10-24

...BRCA1/2 gene mutation (non-BRCA1/2). They were matched to 327 sporadic controls for year and age at detection. To correc...

Mizushina(Yoshiyuki),Nakagawa(Kiyotaka),Shib… Biochem Biophys Res Commun 2006-02-23

...BRCA1 C-terminus (BRCT) domain (residues 133-575, del-1 pol lambda) was dose-dependent, with 50% inhibition observed at ...

Brekelmans(C T M),Seynaeve(C),Menke-Pluymers… Ann Oncol 2006-09-27

...BRCA1-patients (n = 170). All BRCA1-associated patients were matched in a 1:2 ratio for age and year of diagnosis to spo...

Martin(Sarah A),Ouchi(Toru) Cancer Res 2006-01-25

...BRCA1, but not phosphorylation-deficient BRCA1Ser1423Ala/Ser1524Ala (BRCA1(S1423/1524A)). In SNU251 cells expressing BRC...

Wei(Minjie),Grushko(Tatyana A),Dignam(James)… Cancer Res 2006-01-25

...BRCA1 transcripts, which was reversible in the heavily BRCA1-methylated cell line UACC3199 following treatment with 5-az...

Agata(S),Dalla Palma(M),Callegaro(M),Scaini(… J Med Genet 2006-07-24

BRCA1 and BRCA2 are the two major genes responsible for the breast and ovarian cancers that cluster in families with a g...

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