...BRCA1) predispose women to breast and ovarian cancers. BRCA1 is a large protein with multiple functional domains and int...
...BRCA1/2 might be responsible for as much as 10% of all ovarian cancer cases and all families containing either multiple ...
...BRCA1 or BRCA2 genes account for less than 50% of families with breast/ovarian cancer predisposition. The large percenta...
Germ-line mutations in BRCA1 gene account for a substantial proportion of inherited breast and ovarian cancers. Identifi...
...BRCA1 and BRCA2 (BRCA1/2) mutations among African American women.,Participants were 54 African American women at moderat...
...BRCA1, BRCA2, Ku70, and Ku80 and their putative role in patients survival in a large series of colorectal cancer.,342 sp...
Basal-like phenotype tumors are frequently found among BRCA1 germ-line mutated breast carcinomas. They are biologically ...
...BRCA1) nuclear protein contains a tandem globular carboxy terminus domain termed BRCT. The BRCT repeats in BRCA1 are pho...
The role of germline BRCA1 mutations in hereditary breast and ovarian cancer (HBOC) has been well established in women i...
...BRCA1 or BRCA2 mutation, and 127 (47%) of 269 women underwent salpingo-oophorectomy. No occult cancers were found. In ei...
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