...BRCA1/2 and RAD51. Because the genes that participate in the DNA repair pathway have been described as low-penetrance br...
...BRCA1/2 mutation-negative index patients of 592 German BC families and 735 control individuals.,The T allele of rs122553...
...BRCA1 are predisposed to breast and ovarian cancers. Why the BRCA1 protein suppresses tumor development specifically in ...
Among the genes involved in ovarian carcinogenesis, there has been increased interest in tumor-suppressor genes p53 and ...
...BRCA1 or BRCA2 are candidates for bilateral salpingo-oophorectomy (BSO). To address the need for adjustment of the curre...
...BRCA1, CHEK1 and TP53. ATR appears as a good candidate breast cancer susceptibility gene and the current study was desig...
...BRCA1 or BRCA2 mutation carrier status of women at high risk for developing the heritable form of breast and ovarian can...
...BRCA1, and 7470A>G in BRCA2) were detected in both controls and breast cancer patients. Rare BRCA1/2 sequence alteration...
...BRCA1/2 mutation analysis. Sensitivity, specificity, positive and negative predictive values, likelihood ratios and area...
...BRCA1 was positionally cloned in 1994. During the last 12 years, several lines of evidence have implicated BRCA1 in the ...
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