...BRCA1/2 mutation, decisions as to whether to undergo prophylactic risk-reduction surgery may differ from those women who...
...BRCA1-associated proteins may modify both the risk of developing cancers in BRCA1 mutation carriers and the efficacy of ...
...BRCA1 mutation was found in 35% of the tested group, while 30% were BRCA2 carriers. Mean age at intervention was 45.3 ye...
...BRCA1 and BRCA2 account for a large proportion of inherited breast and ovarian cancer. Both genes are involved in DNA re...
...BRCA1 and BRCA2 have not only shed light on the biology of these proteins but have also raised hopes that these data cou...
...brca1. We used the mouse mammary tumor virus (MMTV) promoter to target expression of a kinase-dead CHK2 allele (D347A). ...
...BRCA1, comparing them with the DNA-binding properties of the BRCA1/BARD1 heterodimer. Because nuclear BRCA1 exists as a ...
...BRCA1, and the fact that approximately 80% of tumors from BRCA1 and BRCA2 carriers undergo inactivation of the wild-type...
...BRCA1 mutations. Occupational risks include high temperature environments and exhaust fumes, but electromagnetic fields ...
...BRCA1 among autosomal axes, absence of RAD51 in early and advanced spermatocytes and permanence of gamma-H2AX labelling ...
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