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Genomic instability and cancer: networks involved in response to DNA damage.

Eyfjord(Jorunn Erla),Bodvarsdottir(Sigridur … Mutat Res 2006-08-11

...BRCA1 and BRCA2. Chromosomal instability is a common feature of many human cancers and most of the instability syndromes...

Factors increasing local recurrence in breast-conserving surgery.

Fatouros(Michael),Roukos(Dimitrios H),Arampa… Expert Rev Anticancer Ther 2006-02-07

...BRCA1 or BRCA2 mutations should be informed about the increased risk of contralateral breast cancer and ipsilateral fail...

The breast cancer susceptibility gene BRCA1 regulates progesterone receptor sig…

Ma(Yongxian),Katiyar(Pragati),Jones(Laundett… Mol Endocrinol 2006-03-07

...BRCA1 repression of PR activity. The BRCA1-PR interaction has functional consequences. Thus, we showed that BRCA1 inhibi...

Communication and decision-making about seeking inherited cancer risk informati…

Mellon(Suzanne),Berry-Bobovski(Lisa),Gold(Ro… Psychooncology 2006-08-10

...BRCA1 and BRCA2 have led to new options in genetic risk assessment for families with histories of breast and ovarian can...

The retinoblastoma tumor suppressor protein is required for efficient processin…

Xiao(Hai),Goodrich(David W) Oncogene 2006-03-27

...BRCA1 in intact cells, and pRb is required for association between TOP2 and BRCA1. These results suggest that pRb facili...

Good timing in the cell cycle for precise DNA repair by BRCA1.

Durant(Stephen T),Nickoloff(Jac A) Cell Cycle 2006-06-12

...BRCA1. Heterozygous BRCA1 mutations predispose individuals to breast, ovarian and other secondary cancers. BRCA1-defecti...

The abnormal spindle-like, microcephaly-associated (ASPM) gene encodes a centro…

Zhong(Xueyan),Liu(Limin),Zhao(Ailian),Pfeife… Cell Cycle 2006-06-12

...BRCA1. ASPM localizes to the centrosome in interphase and to the spindle poles from prophase through telophase. These fi...

Histopathological features of breast tumours in BRCA1, BRCA2 and mutation-negat…

Eerola(Hannaleena),Heikkilä(Päivi),Tamminen(… Breast Cancer Res 2006-01-31

...BRCA1/2 tumours are less well known. The aim of this study was to characterise familial non-BRCA1/2 tumours and to evalu...

Psychological impact of genetic testing for cancer susceptibility: an update of…

Meiser(Bettina) Psychooncology 2006-03-10

...BRCA1/2 and HNPCC-related mutations is more consistently related to psychological factors, rather than sociodemographic ...

Genetic, functional, and histopathological evaluation of two C-terminal BRCA1 m…

Lovelock(P K),Healey(S),Au(W),Sum(E Y M),Tes… J Med Genet 2006-12-15

...BRCA1 variants, 5236G>C (G1706A) and 5242C>A (A1708E) on BRCA1 function, and to survey the relative usefulness of severa...

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