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Inhibition of BRCA1 in breast cell lines causes the centrosome duplication cycl…

Ko(M J),Murata(K),Hwang(D-S),Parvin(J D) Oncogene 2006-02-16

...BRCA1 inhibition could occur and then releasing, we found that inhibition of BRCA1 caused centrosome amplification betwe...

Modulation of aromatase expression by BRCA1: a possible link to tissue-specific…

Hu(Yanfen),Ghosh(Sagar),Amleh(Asma),Yue(Wei)… Oncogene 2006-01-12

...BRCA1 increase risks of familial breast and ovarian cancers, particularly among premenopausal women. While BRCA1 plays a...

Aberrant expression of BARD1 in breast and ovarian cancers with poor prognosis.

Wu(Jian-Yu),Vlastos(Anne-Therese),Pelte(Mari… Int J Cancer 2006-03-02

...BRCA1, with which it colocalizes to nuclear dots. Independently of BRCA1, BARD1 can induce p53-dependent apoptosis in re...

Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage…

Brew(Christine T),Aronchik(Ida),Hsu(Jocelyn … Int J Cancer 2006-02-28

...BRCA1. Phosphorylation of p53 at the N-terminus has previously been shown to disrupt the interaction between p53 and its...

Sex ratio distortion in offspring of families with BRCA1 or BRCA2 mutant allele…

Balmaña(Judith),Díez(Orland),Campos(Berta),M… Breast Cancer Res Treat 2006-01-27

There has been controversy regarding whether BRCA1 germline mutations favor female births or whether the sex imbalances ...

Is BRCA1/BRCA2-related breast carcinogenesis estrogen dependent?

Noruzinia(Mehadad),Coupier(Isabelle),Pujol(P… Cancer 2006-01-12

...BRCA1 expression could be induced by estradiol in experimental models, whereas recent studies indicate that BRCA1 modifi...

Predictive genetic testing for hereditary breast and ovarian cancer: psychologi…

Claes(E),Evers-Kiebooms(G),Denayer(L),Decruy… J Genet Couns 2006-03-03

...BRCA1/2 mutations when offered within a multidisciplinary approach. Carriers had higher subjective risk perception of br...

Communication analysis of BRCA1 genetic counseling.

Ellington(Lee),Roter(Debra),Dudley(William N… J Genet Couns 2006-03-03

In this study, we apply an existing medical communication coding system to BRCA1 genetic counseling sessions, describe t...

Pharmacogenomics in lung cancer: an analysis of DNA repair gene expression in p…

García-Campelo(Rosario),Alonso-Curbera(Guill… Expert Opin Pharmacother 2006-06-01

...BRCA1 expression profiling as predictors of anticancer drug efficacy.

Fanconi anemia: current management.

Kook(Hoon) Hematology 2006-06-02

...BRCA1 and BRCA2. Stem cell transplantation (SCT) is the only option for establishing normal hematopoiesis. To reduce und...

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