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Usefulness of predictive tests for cancer treatment.

Rosell(R),Cuello(M),Cecere(F),Santarpia(M)... Bull Cancer 2006-09-21

...BRCA1 mRNA expression is a differential modulator of chemotherapy sensitivity. Low levels predict cisplatin sensitivity ...

Hyperplasia and spontaneous tumor development in the gynecologic system in mi...

Kim(Sang Soo),Cao(Liu),Lim(Sung-Chul),Li(C... Mol Cell Biol 2006-09-28

...BRCA1 locus generates multiple protein products including BRCA1-Delta11, which is identical to the BRCA1 full-length iso...

The 185delAG mutation (c.68_69delAG) in the BRCA1 gene triggers translation r...

Buisson(Monique),Anczuków(Olga),Zetoune(Al... Hum Mutat 2006-10-02

The 185delAG mutation (c.68_69delAG; ter39) in the BRCA1 gene is a founder Jewish Ashkenazi mutation that is carried by ...

Novel germline BRCA1 and BRCA2 mutations in Turkish women with breast and/or ...

Egeli(Unal),Cecener(Gulsah),Tunca(Berrin),... Cancer Invest 2006-11-03

BRCA1 and BRCA2 gene mutations in patients with breast and/or ovarian cancer have been not characterized in the Turkish ...

Risk-reducing surgery, screening and chemoprevention practices of BRCA1 and B...

Phillips(K-A),Jenkins(M A),Lindeman(G J),M... Clin Genet 2006-11-08

...BRCA1 and BRCA2 mutation carriers using a self-report questionnaire. Of 142 unaffected female mutation carriers, 70 (49%...

Diagnostic testing of genetic disorders: limiting the scope of patent claims ...

Abbot(John) J Law Med 2006-12-12

...BRCA1. By examining the application of disclosure requirement by courts in genetic and non-genetic chemical inventions, ...

Identification of a common polymorphism in the TopBP1 gene associated with he...

Karppinen(Sanna-Maria),Erkko(Hannele),Rein... Eur J Cancer 2006-12-18

Besides BRCA1 and BRCA2 other genes are also likely to be involved in hereditary predisposition to breast and/or ovarian...

Differential DNA methylation profiles in gynecological cancers and correlatio...

Yang(Hui-Juan),Liu(Vincent W S),Wang(Yue),... BMC Cancer 2006-11-01

...BRCA1, p14, p15, RIZ1 and TMS1). The frequencies of occurrence of hypermethylation in 4 candidate genes in individual sa...

TopBP1 contains a transcriptional activation domain suppressed by two adjacen...

Wright(Roni H G),Dornan(Edward S),Donaldso... Biochem J 2006-12-27

TopBP1 has eight BRCT [BRCA1 (breast-cancer susceptibility gene 1) C-terminus] domains and is involved in initiating DNA...

A mouse model for the molecular characterization of brca1-associated ovarian ...

Xing(Deyin),Orsulic(Sandra) Cancer Res 2006-11-28

...Brca1 wild-type and Brca1-deficient cells. The Brca1 wild-type and Brca1-deficient mouse ovarian tumors and cell lines p...

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