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[Advance in researches on BRCA1].

Yan(Jing-Hua),Ye(Qi-Nong),Huang(Cui-Fen) Yi Chuan 2006-04-24

...BRCA1 is reviewed, and the role of BRCA1 in cancer development and progression is discussed, that may facilitate potenti...

Histopathological features of breast tumours in BRCA1, BRCA2 and mutation-neg...

Eerola(Hannaleena),Heikkilä(Päivi),Tammine... Breast Cancer Res 2006-01-31

...BRCA1/2 tumours are less well known. The aim of this study was to characterise familial non-BRCA1/2 tumours and to evalu...

Loss of heterozygosity at BRCA1, TP53, nm-23 and other loci on chromosome 17q...

Saleh(Ekram M),Wahab(Abdel Hady A Abdel),E... J Egypt Natl Canc Inst 2006-01-19

...BRCA1 gene, followed by 32% LOH in nm-23 gene. D17S183 and D17S250, which are localised telomeric and centromeric to BRC...

Novel somatic mutations in the BRCA1 gene in sporadic breast tumors.

Janatova(Marketa),Zikan(Michal),Dundr(Pave... Hum Mutat 2006-05-16

Germline mutations in two major susceptibility genes BRCA1 and BRCA2 contribute to the majority of inherited breast and ...

Hereditary breast/ovarian and colorectal cancer genetics knowledge in a natio...

Wideroff(L),Vadaparampil(S T),Greene(M H),... J Med Genet 2006-07-24

...BRCA1/2 mutations, and 33.8% recognised that these mutations occur in <10% of breast cancer patients. Only 13.1% accurat...

Haplotype analysis of common variants in the BRCA1 gene and risk of sporadic ...

Cox(David G),Kraft(Peter),Hankinson(Susan ... Breast Cancer Res 2006-01-31

Truncation mutations in the BRCA1 gene cause a substantial increase in risk of breast cancer. However, these mutations a...

The androgen receptor CAG repeat polymorphism and modification of breast canc...

Spurdle(Amanda B),Antoniou(Antonis C),Duff... Breast Cancer Res 2006-01-31

The androgen receptor (AR) gene exon 1 CAG repeat polymorphism encodes a string of 9-32 glutamines. Women with germline ...

New advances in the DNA damage response network of Fanconi anemia and BRCA pr...

Fei(Peiwen),Yin(Jinhu),Wang(Weidong) Cell Cycle 2006-03-23

...BRCA1 and BRCA2. In response to DNA damage or replication signals, a nuclear FA core complex of at least 6 FA proteins (...

[Quantitative analysis of circulating DNA in serum of cancer patients].

Tu(Hong),Gao(Hai-feng),Fu(Shi-long),Chen(Hao) Zhonghua Zhong Liu Za Zhi 2006-03-17

...BRCA1 (D17S579, D17S855) and p53 (TP53, D17S786) in serum DNA was analyzed by PCR-based method.,SYBR green I dot stainin...

Classification of BRCA1 missense variants of unknown clinical significance.

Phelan(C M),Dapic(V),Tice(B),Favis(R),Kwan... J Med Genet 2006-04-20

BRCA1 is a tumour suppressor with pleiotropic actions. Germline mutations in BRCA1 are responsible for a large proportio...

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