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Large genomic rearrangements of both BRCA2 and BRCA1 are a feature of the inh...

Woodward(A M),Davis(T A),Silva(A G S),Kirk... J Med Genet 2006-04-17

...BRCA1 or BRCA2 and large genomic rearrangements in BRCA1. However, there is little evidence that genomic rearrangements ...

Evolution of the tumor suppressor BRCA1 locus in primates: implications for c...

Pavlicek(Adam),Noskov(Vladimir N),Kouprina... Hum Mol Genet 2006-01-12

...BRCA1 sequence is variable between primates and evolved under positive selection. In contrast, the terminal regions of B...

Satisfaction with genetic counseling for BRCA1 and BRCA2 mutations among Afri...

Charles(Sarah),Kessler(Lisa),Stopfer(Jill ... Patient Educ Couns 2006-12-08

...BRCA1 and BRCA2 (BRCA1/2) mutations among African American women.,Participants were 54 African American women at moderat...

Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts ...

Grabsch(Heike),Dattani(Mit),Barker(Lisa),M... Clin Cancer Res 2006-05-03

...BRCA1, BRCA2, Ku70, and Ku80 and their putative role in patients survival in a large series of colorectal cancer.,342 sp...

Prognostic significance of basal-like phenotype and fascin expression in node...

Rodríguez-Pinilla(Socorro María),Sarrió(Da... Clin Cancer Res 2006-05-03

Basal-like phenotype tumors are frequently found among BRCA1 germ-line mutated breast carcinomas. They are biologically ...

Partnering in oncogenetic research--the INHERIT BRCAs experience: opportuniti...

Avard(Denise),Bridge(Peter),Bucci(Lucie M)... Fam Cancer 2006-06-22

...BRCA1 and BRCA2 mutations and their deleterious impact upon different populations; (b) to pinpoint novel breast cancer s...

BRCA1 and BRCA2 mutations in breast and ovarian cancer syndrome: reflection o...

Sinilnikova(Olga M),Mazoyer(Sylvie),Bonnar... Fam Cancer 2006-06-22

...BRCA1 and BRCA2, we report the current status of these families and compare the observed BRCA1/2 mutation detection rate...

An analysis of unclassified missense substitutions in human BRCA1.

Tavtigian(Sean V),Samollow(Paul B),de Silv... Fam Cancer 2006-06-22

...BRCA1 missense substitutions, the BRCA1-with-BRCA2 Ascertainment Ratio. Here, we complement these measures with a more p...

Insights into the molecular basis of human hereditary breast cancer from stud...

Glover(J N Mark) Fam Cancer 2006-06-22

...BRCA1 are essential for the tumor suppressor function of this protein. Here we review structural and functional studies ...

The European opposition against the BRCA gene patents.

Matthijs(Gert) Fam Cancer 2006-06-22

In 2001, the European Patent Organisation (EPO) granted 3 patents on the BRCA1 gene (EP-B-699754, EP-B-705903, EP-B-7059...

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