...BRCA1 and BRCA2. The most advanced mouse models for BRCA1- and BRCA2-associated tumorigenesis mimic human disease to the...
...BRCA1 mutations. Haplotype analyses suggested founder effects for 3 of these. The prevalence of BRCA1 or BRCA2 mutations...
...BRCA1/2 mutations in AJ families, and Myriad II was most sensitive in non-AJ families. The Manchester Scoring System was...
...BRCA1/2 mutations. Cases and controls showed a similar genotype distribution and the SNP did not seem to modify the age ...
...BRCA1 or BRCA2 mutation carriers.,We identified 1600 cases of breast cancer and 1600 controls without breast cancer who ...
...BRCA1, p53, and WT1, whose mechanism of action involves regulation of IGF-IR gene expression.
...BRCA1/2 and RAD51. Because the genes that participate in the DNA repair pathway have been described as low-penetrance br...
...BRCA1 and BRCA2) are responsible for less than 5% of all breast cancer cases. Many studies have shown that the cancer ri...
...Brca1(delta11/delta11)p53+/- mice, lifespan of Brca1(delta11/delta11)Chk2-/- mice was remarkably extended. Analysis of B...
...BRCA1-associated group (p = 0.385).,Our data do not support the association between copy number gain at 2q24-32 and BRCA...
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