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TP53 BRCA1 CRISPR single-cell cancer

Jernström(Helena),Sellberg(Gunilla),Borg(A... Eur J Cancer Prev 2006-12-01

...BRCA1/2 families and from families in which no BRCA1/2 mutations could be detected, that is, from BRCAX families. One hu...

van der Hout(Annemarie H),van den Ouweland... Hum Mutat 2006-08-07

...BRCA1 (11.5%), 197 in BRCA2 (4.9%), and in two index cases a deleterious change in both BRCA1 and BRCA2 was identified. ...

Kluzek(Katarzyna),Zdzienicka(Małgorzata Z) Postepy Biochem 2006-06-01

...BRCA1, BRCA2, ATM or NBS1. Moreover, BRCA2 that plays a crucial role in homologous recombination is one of FA proteins. ...

Chen(Yinghua),Borowicz(Stanley),Fackenthal... Biochem Biophys Res Commun 2006-07-11

BRCA1 is a large protein that exhibits a multiplicity of functions in its apparent role in DNA repair. Certain mutations...

Fiala(Kevin A),Duym(Wade W),Zhang(Jun),Suo... J Biol Chem 2006-08-21

...BRCA1 C-terminal domain, and a previously uncharacterized proline-rich domain. Strikingly, pre-steady-state kinetic anal...

Le-Petross(Huong T) J Natl Compr Canc Netw 2006-10-25

...BRCA1 and BRCA2 mutations. Recent studies show improved specificity of MRI, likely related to advances in technique and ...

Damaraju(Sambasivarao),Murray(David),Dufou... Clin Cancer Res 2006-10-30

...BRCA1, BRCA2, ESR1, XRCC1, XRCC2, XRCC3, NBN, RAD51, RAD52, LIG4, ATM, BCL2, TGFB1, MSH6, ERCC2, XPF, NR3C1, CYP1A1, CYP...

Chabalier(C),Lamare(C),Racca(C),Privat(M),... Cell Cycle 2006-06-05

BRCA1 germline mutations predispose women to early onset, familial breast and ovarian cancer. BRCA1 has been recently im...

Thomassen(Mads),Gerdes(Anne-Marie),Cruger(... Cancer Genet Cytogenet 2006-08-18

Germline mutations in BRCA1 and BRCA2 predispose female carriers to breast and ovarian cancer. The majority of mutations...

Furuta(Saori),Wang(Ju-Ming),Wei(Shuanzeng)... Cancer Cell 2006-09-11

...BRCA1 and CtIP based on microarray analysis of mammary epithelial cells in 3D culture. BRCA1, CtIP, and ZBRK1 form a com...

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