Germline mutations of BRCA1 and BRCA2 increase the risk for breast cancer. Mutation carriers selecting breast-conservati...
...BRCA1 and BRCA2, is now available in a clinical setting.
...BRCA1 and/or BRCA2 dysfunction. It most likely arises from epithelium within inclusion cysts or from the surface of the ...
BRCA1 and BRCA2 genes are responsible for 5-10% of breast and ovarian cancer cases. However, the vast majority of ovaria...
...BRCA1-IRIS mRNA and protein. Furthermore, the level of over-expression of BRCA1-IRIS in ERalpha-negative cell lines even...
...BRCA1 (Brca1Delta11/Delta11) display both increased tumorigenesis and premature aging, yet molecular mechanisms underlyi...
...BRCA1 in the disease-free sample group, whereas such functional coordination is absent in the samples from patients who ...
Breast cancer is one of the major killers worldwide. The objectives of this study were to determine the frequency of BRC...
...BRCA1 and mitotic regulators such as Aurora A, Nek2 and the Polo-like kinases Plk1 and Plk3. However, many missing links...
...BRCA1/BARD1 to impact on diverse cellular processes. It is clear that the E3-Ub ligase activity of BRCA1/BARD1 is of cri...
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