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The prevalence of germline BRCA1 and BRCA2 mutations in young women with brea...

Golshan(Mehra),Miron(Alex),Nixon(Asa J),Ga... Am J Surg 2006-07-18

Germline mutations of BRCA1 and BRCA2 increase the risk for breast cancer. Mutation carriers selecting breast-conservati...

[Breast cancer screening different from that used for the general population:...

Chappuis(P O) Rev Med Suisse 2006-07-20

...BRCA1 and BRCA2, is now available in a clinical setting.

Molecular pathology of epithelial ovarian cancer.

Christie(Michael),Oehler(Martin K) J Br Menopause Soc 2006-08-08

...BRCA1 and/or BRCA2 dysfunction. It most likely arises from epithelium within inclusion cysts or from the surface of the ...

Are CYP17 genotypes a biomarker for ovarian cancer in patients with cancer hi...

Yazici(Hulya),Tigli(Hulya),Kadehci(Zuleyha... Oncol Res 2006-08-29

BRCA1 and BRCA2 genes are responsible for 5-10% of breast and ovarian cancer cases. However, the vast majority of ovaria...

BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells.

Nakuci(Enkeleda),Mahner(Sven),Direnzo(Jame... Exp Cell Res 2006-10-24

...BRCA1-IRIS mRNA and protein. Furthermore, the level of over-expression of BRCA1-IRIS in ERalpha-negative cell lines even...

Absence of the full-length breast cancer-associated gene-1 leads to increased...

Shukla(Vivek),Coumoul(Xavier),Cao(Liu),Wan... Cancer Res 2006-09-19

...BRCA1 (Brca1Delta11/Delta11) display both increased tumorigenesis and premature aging, yet molecular mechanisms underlyi...

Computational exploration of the activated pathways associated with DNA damag...

Wen(Liting),Li(Wei),Sobel(Marc),Feng(Jin-a... Proteins 2006-09-21

...BRCA1 in the disease-free sample group, whereas such functional coordination is absent in the samples from patients who ...

Analysis of RAD51 polymorphism and BRCA1 mutations in Polish women with breas...

Romanowicz-Makowska(H),Smolarz(B),Zadrozny... Exp Oncol 2006-09-15

Breast cancer is one of the major killers worldwide. The objectives of this study were to determine the frequency of BRC...

Structure meets function--centrosomes, genome maintenance and the DNA damage ...

Löffler(Harald),Lukas(Jiri),Bartek(Jiri),K... Exp Cell Res 2006-09-11

...BRCA1 and mitotic regulators such as Aurora A, Nek2 and the Polo-like kinases Plk1 and Plk3. However, many missing links...

BRCA1-mediated ubiquitylation.

Boulton(Simon J) Cell Cycle 2006-10-04

...BRCA1/BARD1 to impact on diverse cellular processes. It is clear that the E3-Ub ligase activity of BRCA1/BARD1 is of cri...

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