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Genomic rearrangements at the BRCA1 locus in Spanish families with breast/ova...

de la Hoya(Miguel),Gutiérrez-Enríquez(Sara... Clin Chem 2006-08-29

...BRCA1 LGR have been observed among populations. Here we report the first comprehensive analysis of BRCA1 LGRs conducted ...

A role for XRCC4 in age at diagnosis and breast cancer risk.

Allen-Brady(Kristina),Cannon-Albright(Lisa... Cancer Epidemiol Biomarkers... 2006-11-14

...BRCA1/2 mutation negative from high-risk Utah pedigrees. We observed a significant association for two 4-locus tSNP hapl...

Loss of heterozygosity analysis in ductal lavage samples from BRCA1 and BRCA2...

Antill(Yoland C),Mitchell(Gillian),Johnson... Cancer Epidemiol Biomarkers... 2006-11-14

...BRCA1/2 loci in DL samples from BRCA1/2 mutation carriers, while also assessing the effect of DNA quantity.,DNA yield wa...

Loss of heterozygosity at the BRCA1 and BRCA2 loci detected in ductal lavage ...

Locke(Imogen),Kote-Jarai(Zsofia),Bancroft(... Cancer Epidemiol Biomarkers... 2006-11-14

...BRCA1/2 loci and compared with that at a control locus (APC) using free DNA from the ductal lavage fluid of BRCA carrier...

Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal...

Finch(Amy),Beiner(Mario),Lubinski(Jan),Lyn... JAMA 2006-07-18

Women with BRCA1 or BRCA2 mutation are often advised to undergo preventive oophorectomy. The effectiveness of this inter...

BRCA1 at the crossroad of multiple cellular pathways: approaches for therapeu...

Yarden(Ronit I),Papa(Moshe Z) Mol Cancer Ther 2006-10-04

...BRCA1. The long-term goal has been to identify the biochemical pathways reliant on BRCA1 that can be exploited for devel...

BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP.

Yu(Xiaochun),Fu(Shuang),Lai(Maoyi),Baer(Ri... Genes Dev 2006-08-23

...BRCA1 BRCT domains specifically recognize phospho-serine motifs. Here, we demonstrate that BRCA1 Ring domain catalyzes C...

[Familial breast cancer: what the radiologist needs to know].

Kuhl(C K) Rofo 2006-08-16

...BRCA1-associated breast cancer may be indistinguishable from fibroadenomas: they appear as well-defined, roundish, hypoe...

Genetics and the young woman with breast cancer.

Evans(James P),Skrzynia(Cécile),Susswein(L... Breast Dis 2006-08-31

...BRCA1 or BRCA2, both identified about 10 years ago, are responsible for the majority of inherited breast cancer. By virt...

Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients wit...

Karppinen(S-M),Barkardottir(R B),Backenhor... J Med Genet 2006-12-15

...BRCA1-interacting protein but has also been described in tumour-suppressive functions independent of BRCA1. Several stud...

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