...BRCA1 LGR have been observed among populations. Here we report the first comprehensive analysis of BRCA1 LGRs conducted ...
...BRCA1/2 mutation negative from high-risk Utah pedigrees. We observed a significant association for two 4-locus tSNP hapl...
...BRCA1/2 loci in DL samples from BRCA1/2 mutation carriers, while also assessing the effect of DNA quantity.,DNA yield wa...
...BRCA1/2 loci and compared with that at a control locus (APC) using free DNA from the ductal lavage fluid of BRCA carrier...
Women with BRCA1 or BRCA2 mutation are often advised to undergo preventive oophorectomy. The effectiveness of this inter...
...BRCA1. The long-term goal has been to identify the biochemical pathways reliant on BRCA1 that can be exploited for devel...
...BRCA1 BRCT domains specifically recognize phospho-serine motifs. Here, we demonstrate that BRCA1 Ring domain catalyzes C...
...BRCA1-associated breast cancer may be indistinguishable from fibroadenomas: they appear as well-defined, roundish, hypoe...
...BRCA1 or BRCA2, both identified about 10 years ago, are responsible for the majority of inherited breast cancer. By virt...
...BRCA1-interacting protein but has also been described in tumour-suppressive functions independent of BRCA1. Several stud...
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