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Liu(Y),Jiang(X),Sun(J),Wang(L),Li(J),Liu(H... Int J Mol Sci 2026-06-12

...Brca1. Gene set enrichment analysis further confirms significant suppression of the HR-dependent DSB repair pathway. Mec...

Chua(VXY),Yip(JMX),Cho(MTK),Lin(SZQ),Tan(R... Int J Mol Sci 2026-06-12

...BRCA1/MDC1 in humans). We propose that Tpi1p and Tdh1-3p override Rad9p, allowing cells with damaged DNA to proliferate....

Suvorova(Y),Monakhova(A),Chekanov(N),Musha... Int J Mol Sci 2026-06-13

...BRCA1 (151 variants), BRCA2 (100), RYR1 (93), and LDLR (71). In addition, we found 238 potential loss-of-function varian...

Robaczyńska(J),Kiljańczyk(M),Maj(M),Kiljań... Int J Mol Sci 2026-06-19

...BRCA1 variants remains unclear and continues to be actively investigated. Clarifying this relationship could have signif...

Buckley-Benbow(L),Ozgencil(M),Tardocchi(A)... NAR Cancer 2026-06-00

...BRCA1/BRCA2-mutated cancers. Despite this, acquired resistance to PARPi has become a major challenge in the clinic. Henc...

Takuwa(H),Sasaki(S),Goda(N),Takeuchi(M) Front Oncol None

...BRCA1/2 genetic testing identified a pathogenic variant in BRCA1. The patient had previously lost her fourth child due t...

Kasi(A),Al-Rajabi(RMT),Baranda(JC),Saeed(A... Oncologist 2026-07-08

...BRCA1/2 germline mutation-positive patient group (n = 14) reported a 6-month PFS rate of 50% and a median overall surviv...

Beasley(HK),Shah(T),Tinker(RJ),Weidner(A),... Cancer 2026-06-15

...BRCA1 carriers (23.6% vs. 75.5%; p < .001), and family history of breast cancer was significantly more frequent among BR...

Arab(W),Kassis(NE),Khoury(C),Mansour(H),Ch... Gynecol Oncol Rep 2026-06-00

...BRCA1 mutation was identified on tumor sequencing and was subsequently confirmed as a germline pathogenic variant. Compl...

Ma(F),Xu(B),China Anti‐Cancer Association ... Cancer Innov 2026-06-00

...BRCA1/2 mutations. By selectively inhibiting DNA repair in tumor cells, these agents induce a "synthetic lethality" effe...