...BRCA1, and changes in trans-acting regulators can affect the expression of genes such as Ron, RAC1 and CD44.
The BRCA1 tumor suppressor gene encodes a phosphoprotein involved in many cellular key functions including DNA repair, t...
Inherited mutations of the BRCA1 gene (chromosome 17q21), a tumor suppressor, lead to an increased risk of breast cancer...
...BRCA1) were associated with altered risk of NHL and diffuse large B-cell lymphoma (DLBCL), the major B cell subtype. In ...
...BRCA1 functions differentially to modulate the chemosensitivity of cancer cells.,To clarify these findings, BRCA1 expres...
...BRCA1 or BRCA2 mutation carriers. These germline mutation carriers face an increased lifetime risk of a second primary b...
...BRCA1, confer selective resistance to cisplatin or taxanes, whereas thioredoxin confers a broad spectrum of chemoresista...
...BRCA1, six (9.6%) had variants of unclear significance, eight (13%) had deleterious mutations. BRCA1-associated breast c...
...BRCA1 and BRCA2 in patients with family history was 11.4% and 2.9%, respectively.,Two novel mutations in BRCA1 may be mu...
...BRCA1) associates with the BRCA1-associated RING domain-1 protein (BARD1) to form a heterodimer, which exhibits ubiquiti...
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