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Increased level of chromosomal damage after irradiation of lymphocytes from B...

Kote-Jarai(Z),Salmon(A),Mengitsu(T),Copela... Br J Cancer 2006-03-14

...BRCA1 has a role in DNA damage surveillance. Our finding has implications for treatment and screening of BRCA1 mutation ...

Bilateral risk-reducing oophorectomy in BRCA1 and BRCA2 mutation carriers.

Domchek(Susan M),Stopfer(Jill E),Rebbeck(T... J Natl Compr Canc Netw 2006-05-26

...BRCA1 and BRCA2 (BRCA1/2) mutations. BRRO significantly reduces breast cancer risk by approximately 50% and ovarian canc...

Cofactor of BRCA1: a novel transcription factor regulator in upper gastrointe...

McChesney(Patricia A),Aiyar(Sarah E),Lee(O... Cancer Res 2006-03-21

...BRCA1 (COBRA1) is a newly characterized member of the negative elongation factor (NELF) complex. In this work, we show t...

Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promo...

Wang(Hui-Chun),Chou(Wen-Cheng),Shieh(Sheau... Cancer Res 2006-03-21

...BRCA1, and tested the hypothesis that ATM and Chk2 promote precise end-joining by BRCA1. Support for this hypothesis cam...

Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity ...

Zhuang(Jing),Zhang(Junran),Willers(Henning... Cancer Res 2006-03-21

...BRCA1, or by expression of a dominant-negative kinase-dead Chk2 mutant in cells with WT BRCA1. We suggest that the diffe...

Mammographic density and breast cancer risk in BRCA1 and BRCA2 mutation carri...

Mitchell(Gillian),Antoniou(Antonis C),Warr... Cancer Res 2006-03-21

...BRCA1 and BRCA2 mutations is unclear. We obtained mammograms from 206 female carriers of BRCA1 or BRCA2 mutations, 96 of...

[Prophylactic oophorectomy among carriers of BRCA1/2 mutations--demographic a...

Daum(Hagit),Sagi(Michal),Pikarsky(Eli),Pru... Harefuah 2006-03-02

...BRCA1/2 mutations that underwent prophylactic salpingo-oophorectomy. We also examined the pathological specimens and poi...

Sharing BRCA1/2 test results with first-degree relatives: factors predicting ...

Patenaude(Andrea Farkas),Dorval(Michel),Di... J Clin Oncol 2006-02-13

...BRCA1/2 test results to first-degree relatives (FDRs) among women tested in a clinical protocol.,A total of 273 women co...

Optimal selection of individuals for BRCA mutation testing: a comparison of a...

James(Paul A),Doherty(Rebecca),Harris(Mari... J Clin Oncol 2006-02-13

...BRCA1 or BRCA2 genes. We examined the performance of six different methods with the aim of identifying an optimal strate...

Aqueous compatible polymers in bionanotechnology.

Carter(S R),Rimmer(S) IEE Proc Nanobiotechnol 2006-03-14

...BRCA1. An overview of both of these areas of research is described outlining the diversity of these aqueous compatible p...

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