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5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda ...

Mizushina(Yoshiyuki),Yagita(Etsuko),Kuramo... Arch Biochem Biophys 2006-04-27

...BRCA1 C-terminus domain (133-575, del-1 pol lambda) and another truncated pol lambda lacking the N-terminal proline-rich...

Effects of oestrogens and anti-oestrogens on normal breast tissue from women ...

Bramley(M),Clarke(R B),Howell(A),Evans(D G... Br J Cancer 2006-05-10

...BRCA1 and BRCA2 genes. The effects of oestradiol (E2), tamoxifen (TAM) and fulvestrant (FUL) on proliferation and steroi...

Identification of BAF57 mutations in human breast cancer cell lines.

Kiskinis(Evangelos),García-Pedrero(Juana M... Breast Cancer Res Treat 2006-10-26

...BRCA1 gene. This locus has been associated with frequent loss of heterozygosity (LOH) and allelic imbalance in breast ca...

Mutational hotspots in the TP53 gene and, possibly, other tumor suppressors e...

Glazko(Galina V),Babenko(Vladimir N),Kooni... Biol Direct 2006-04-26

...BRCA1, BRCA2, and p16. Elucidation of the origin of the hotspots in these genes requires more data on somatic mutations ...

Familial clustering of site-specific cancer risks associated with BRCA1 and B...

Simchoni(Sharon),Friedman(Eitan),Kaufman(B... Proc Natl Acad Sci U S A 2006-04-17

Inherited mutations in BRCA1 and BRCA2 lead to significantly increased risks of breast and ovarian cancer. We used epide...

DNA methylation of multiple tumor-related genes in association with overexpre...

Peng(Dun-Fa),Kanai(Yae),Sawada(Morio),Ushi... Carcinogenesis 2006-08-01

...BRCA1, GSTP1, TIMP-3, CDH1 and DAPK-1 genes. The prevalence of DNA methylation of at least one of the 12 genes and the a...

Breast cancer screening, outside the population-screening program, of women f...

Jacobi(Catharina E),Nagelkerke(Nico J D),v... Cancer Epidemiol Biomarkers... 2006-07-19

...BRCA1/BRCA2 mutations, because current criteria for screening healthy women from breast cancer families are not evidence...

RNASEL mutation screening and association study in Ashkenazi and non-Ashkenaz...

Orr-Urtreger(Avi),Bar-Shira(Anat),Bercovic... Cancer Epidemiol Biomarkers... 2006-07-19

...BRCA1 185delAG founder mutation, which originated hundreds of years earlier. Taken together, our analysis does not suppo...

Applications of genomics in NSCLC.

Rosell(Rafael),Cobo(Manuel),Isla(Dolores),... Lung Cancer 2006-04-11

...BRCA1, are also central to cisplatin resistance.

A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-direct...

Brzovic(Peter S),Lissounov(Alexei),Christe... Mol Cell 2006-04-26

...BRCA1.

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