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Pai(AKA),Dcunha(L),Gopalakrishnan(AP),Umma... Front Syst Biol None

...BRCA1, RAD51AP1, NBN, PNKP, TP53BP1, and PBRM1. UALCAN analysis further revealed differential regulation of SMG1 phospho...

Alsaati(B),Ujaimi(R),Trabulsi(N),Abusanad(... Case Rep Oncol None

...BRCA1/2 testing was negative. She underwent four cycles of neoadjuvant doxorubicin/cyclophosphamide with limited respons...

Zhan(B),Zhong(Y),Chen(X),Dai(Y),Du(L),Lin(... Bioorg Chem 2026-08-18

...BRCA1/2-mutant tumors, has emerged as an effective strategy for cancer therapy. GEN1, a structure-selective endonuclease...

Wang(J),Lu(Z),Ge(M),Zhang(X),Chen(D),Peng(... Clin Lung Cancer 2026-07-27

...BRCA1 being particularly prominent. Immunologically, LOLC tumors exhibited higher TMB and PD-L1 positivity. Integrated p...

Kamath(V),Pai(V),Bhat(B),K S(C),Nayak(PG),... Curr Top Med Chem 2026-08-03

...BRCA1/2 mutations, where further failure of DNA repair results in cell sensitization. Building on the concept of synthet...

Törnblom(A),He(C),Bolin(M),Tzortzakakis(A)... EJNMMI Res 2026-08-19

...BRCA1/2 mutations. However, not all patients respond to these drugs, and therapy-predictive biomarkers are needed to opt...

Alzate(D),Sánchez(AY),Pacheco(Y),Isaza Rug... PLoS One None

...BRCA1. These genes are involved in the molecular pathway of DNA repair by homologous recombination (HRD). Our results de...

Xue(Y),Rashed(FB),Mao(DYL),Abe(KT),Lin(ZY)... Mol Cell 2026-08-24

...BRCA1 and BRCA2 deficiency. Homologous recombination (HR)-deficient tumors upregulate DDIAS to enable HR-deficient cells...

Tsukada(K),Lototska(L),Tsukada(A),Sarusie(... Cell 2026-08-24

...BRCA1-/BRCA2-deficient cells. We also identify biallelic inactivating mutations in DDIAS in patients with a severe neuro...

Barsch(M),Bengsch(B) Dtsch Med Wochenschr 2026-08-00

...BRCA1/2 or PALB2 variants. Biliary tract cancer is therefore a clinically useful model for precision oncology: anatomica...