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TP53 BRCA1 CRISPR single-cell cancer

Zhang(Yiyu),Fan(Saijun),Meng(Qinghui),Ma(Y... J Biol Chem 2005-11-30

...BRCA1 and reduced their ability to rescue BRCA1 inhibition of ER-alpha. E6 and E7 also antagonized the ability of BRCA1 ...

Laakso(Mervi),Loman(Niklas),Borg(Ake),Isol... Mod Pathol 2005-12-16

...BRCA1-associated tumors, but only one of 15 BRCA2-associated tumors was positive for CK5/14. In contrast to sporadic CK5...

Vu-Nishino(Ha),Tavassoli(Fattaneh A),Ahren... Int J Radiat Oncol Biol Phy... 2005-08-25

...BRCA1/2 mutations compared with screened patients in the control group (50.0% vs. 15.8%, p = 0.0035). The medullary coho...

Wardrop(Stacey L),Brown(Melissa A), Genomics 2005-10-18

...BRCA1) revealed two evolutionarily conserved noncoding sequences (CNS) in intron 2, 5 kb downstream of the core BRCA1 pr...

Chen(Li),Madura(Kiran) Cancer Res 2005-09-07

...BRCA1 and BRCA2, are linked to protein degradation. To investigate the involvement of the Ub/proteasome system in breast...

Kleiman(Frida E),Wu-Baer(Foon),Fonseca(Dan... Genes Dev 2005-06-20

...BRCA1/BARD1 ubiquitin ligase activity. Significantly, siRNA-mediated knockdown of BRCA1 and BARD1 resulted in stabilizat...

Yang(Yun-Gui),Herceg(Zdenko),Nakanishi(Koj... Carcinogenesis 2005-11-08

...BRCA1, RAD51 and the MRE11/RAD50/NBS1 complex, suggesting that the FA complex may be involved in the repair of DNA doubl...

Al-Wahiby(S),Slijepcevic(P) Cytogenet Genome Res 2005-07-12

...BRCA1 mutation. Finally, we analyzed mouse embryonic stem cells lacking functional Brca1 and observed the presence of te...

Vézina(Hélène),Durocher(Francine),Dumont(M... Hum Genet 2005-10-11

...BRCA1 recurrent R1443X mutant allele. A highly conserved haplotype, observed in 18 French-Canadian families and generate...

Antoniou(Antonis C),Goldgar(David E),Andri... Genet Epidemiol 2005-11-01

...BRCA1/2 Carrier Cohort Study (IBCCS). Simulations demonstrate that the method gives rate ratio estimates that are close ...

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