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TP53 BRCA1 CRISPR single-cell cancer

Simpson(Kaylene J),Wati(Mas R),Deans(Andre... Int J Dev Biol 2005-04-22

The breast cancer susceptibility gene Brca1 encodes a large multi-functional protein which is implicated as a caretaker ...

Chen(Kai-Shun),Gould(Michael N) Biotechniques 2005-06-21

...Brca1, Brca2, and Adenomatosis polyposis coli (Apc) genes from N2 rats of Brca1 and Brca2 knockouts and (Atm x ApcMin/+)...

Szántó(J),András(C),Tsakiris(J),Gomba(S),S... Breast 2005-02-08

...BRCA1-2 mutations were detected, no further radio- or chemotherapy was performed. A "wait-and-see" policy was decided on...

Mark(Wen-Ying),Liao(Jack C C),Lu(Ying),Aye... J Mol Biol 2005-01-11

...BRCA1. Our results show that although there are a few small, mildly protease-resistant regions, the majority of the BRCA...

Rafnar(Thorunn),Benediktsdottir(Kristrun R... Eur J Cancer 2005-02-14

A single founder mutation in each of the BRCA genes has been identified in Iceland. The frequency of the BRCA1 G5193A an...

Hedau(Suresh),Jain(Neeraj),Husain(Syed A),... Breast Cancer Res Treat 2005-03-15

...BRCA1 gene. None of the 100 sporadic breast cancer patients revealed any protein truncating or deleterious BRCA1 or BRCA...

Au(Wendy W Y),Henderson(Beric R) J Biol Chem 2005-04-08

...BRCA1 to DNA damage-induced foci have not been identified. Here, we mapped the BRCA1 foci-targeting domains of yellow fl...

Aghmesheh(Morteza),Nesland(Jahn M),Kaern(J... Gynecol Oncol 2005-01-25

...BRCA1-linked ovarian tumorigenesis. In the few studies directly comparing p53 mutations in BRCA1-linked and sporadic ova...

Turner(James M A),Mahadevaiah(Shantha K),F... Nat Genet 2005-02-07

...BRCA1 is implicated in this silencing, mirroring its role in the meiotic silencing of the X and Y chromosomes in normal ...

Glover(J N Mark),Williams(R Scott),Lee(Meg... Trends Biochem Sci 2005-08-23

...BRCA1 contains a pair of tandem BRCA1 C-terminal (BRCT) repeats that are essential for the tumour suppressor function of...

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