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Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and u...

Chen(Ceshi),Sun(Xiaodong),Ran(Qimei),Wilki... Oncogene 2005-05-31

...BRCA1, HIF-1alpha, etc. The Kruppel-like factor 5 (KLF5) transcription factor regulates biological processes involved in...

BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation.

Yan(Ying),Spieker(Rebecca S),Kim(Min),Stoe... Oncogene 2005-05-31

...BRCA1-mediated G2/M checkpoint response. In this study, we assessed the role of ERK1/2 kinases in the regulation of BRCA...

Prophylactic mastectomy: indications, options, and reconstructive alternative...

Spear(Scott L),Carter(Mary Ella),Schwarz(K... Plast Reconstr Surg 2005-11-10

...BRCA1 and BRCA2 have become increasingly important in determining risk; a BRCA1-positive patient's risk of developing br...

Pressure overload and neurohumoral activation differentially affect the myoca...

Schott(Peter),Singer(Silke S),Kögler(Haral... Proteomics 2005-09-30

...BRCA1) that is involved in myocardial hypertrophy. Furthermore, we demonstrate that increased afterload-induced hypertro...

Identification of germline BRCA1 and BRCA2 genetic alterations in Greek breas...

Kataki(A),Gomatos(Ip),Pararas(N),Armakolas... Clin Genet 2005-06-16

...BRCA1 missense mutations, one novel BRCA1 intronic deletion, three novel (previously reported) BRCA2 truncating mutation...

Low frequency of CHEK2 1100delC allele in Australian multiple-case breast can...

Jekimovs(C R),Chen(X),Arnold(J),Gatei(M),R... Br J Cancer 2005-03-24

...BRCA1 and BRCA2. Only two (0.6%) index cases heterozygous for the CHEK2 mutation were identified. All available relative...

Coinheritance of BRCA1 and BRCA2 mutations with Fanconi anemia and Bloom synd...

Koren-Michowitz(M),Friedman(E),Gershoni-Ba... Am J Hematol 2005-04-04

...BRCA1 and BRCA2. These two genes, when mutated, play important roles in familial breast and ovarian carcinogenesis. The ...

Prevalence of BRCA1 and BRCA2 mutations in women diagnosed with ductal carcin...

Claus(Elizabeth B),Petruzella(Stacey),Matl... JAMA 2005-03-01

...BRCA1 and BRCA2 mutations in women diagnosed with noninvasive breast carcinoma is unknown.,To estimate the BRCA1 and BRC...

Accuracy of cancer family histories: comparison of two breast cancer syndrome...

Schneider(Katherine A),DiGianni(Lisa M),Pa... Genet Test 2005-04-01

...BRCA1 family, higher education level, female historian, degree of closeness to affected relative, and having fewer than ...

Implications of the age range in a population-based BRCA1 testing program wit...

Bajdik(Chris D),Raboud(Janet M),McGillivra... Genet Test 2005-04-01

The current options available to BRCA1 mutation carriers can be classified as either cancer risk reduction or increased ...

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