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Sustained benefit of adjuvant olaparib in women with germline BRCA1- and BRCA...

Garber(JE),Cameron(D),Campbell(C),Yothers(... Ann Oncol 2026-08-24

...BRCA1 or BRCA2 (gBRCApv) germline variants and high-risk human epidermal growth factor receptor 2 (HER2)-negative early ...

A Rare Case of Pleural Deciduoid Mesothelioma With Histological, Immunohistoc...

Sonobe(H),Omote(R),Niman(E),Takahashi(K),N... Cureus 2026-07-00

...BRCA1-associated protein 1, methylthioadenosine phosphorylase, and merlin/neurofibromatosis 2. Furthermore, cyclin-depen...

Racial and ethnic disparities in enrollment for clinical trials of poly (ADP-...

Kheirkhah Rahimabad(P),Sekhon(S),John(E) Cancer Causes Control 2026-08-25

Poly (ADP-ribose) polymerase (PARP) inhibitors have shown promise in treating breast cancer with BRCA1/2 mutations, part...

Oxidative stress and cancer: current insights and therapeutic implications.

Escribano-Cebrián(M),Bataller(M),Biasini(M... Redox Biol 2026-08-22

...BRCA1), allowing tumorigenesis and drug resistance. They also modulate the tumor microenvironment (TME) by altering tumo...

RNA splicing evidence enables robust classification of BRCA1 exon 18 variants...

Domènech-Vivó(J),Tubeuf(H),Mesman(RLS),Dro... Am J Hum Genet 2026-08-25

...BRCA1 exon 18. The absence of systematic RNA-based assessment for these variants has led to inconsistent interpretation,...

Pregnancy after breast cancer: obstetrics and feto-maternal outcomes.

Fabiani(C),Sanna(F),Guarino(A),Sperduti(I)... Eur Rev Med Pharmacol Sci 2026-08-00

...BRCA1/2-mutated patients. Despite this, the estimated pregnancy achievability in BC survivors is significantly inferior ...

Impact of leuprolide and goserelin on androgen suppression and adverse events...

Freitas(CSM),Rocha-Silva(F),Marques-Silva(... Can J Urol 2026-08-21

...BRCA1, BRCA2, and ATM genes. All treatment groups exhibited significant reductions in PSA and testosterone levels. Leupr...

Olaparib as the first-line maintenance therapy in advanced-stage epithelial o...

Tang(WJ),Chang(SH),Chang(CB),Chen(WC),Wang... Taiwan J Obstet Gynecol 2026-09-00

...BRCA1/2-mutated epithelial ovarian cancer treated at Chang Gung Memorial Hospital, Linkou, between 2019 and 2025. Eligib...

Risk of breast cancer after ovarian cancer in germline BRCA1/2 heterozygotes.

Morgan(RD),Woodward(ER),Evans(DG) J Med Genet 2026-08-25

Breast cancer risk after ovarian cancer in germline BRCA1/2 heterozygotes remains uncertain, with a recent large multice...

Selaginella bryopteris-derived silver nanoparticles against ovarian cancer ce...

Dey(S),Wadhwa(K),Kumari(N),Pandey(C),Kumar... Front Pharmacol None

...BRCA1/2-mutated cancer cells leads to apoptosis. We synthesized silver nanoparticles (AgNPs) from S. bryopteris leaf ext...

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