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TP53 BRCA1 CRISPR single-cell cancer

Palacios(José),Honrado(Emiliano),Osorio(An... Breast Cancer Res Treat 2005-05-19

Familial breast cancers that are associated with BRCA1 or BRCA2 germline mutations differ in both their morphological an...

Pyrpassopoulos(Serapion),Ladopoulou(Angela... Biophys Chem 2005-08-29

Reduced stability of the tandem BRCT domains of human BReast CAncer 1 (BRCA1) due to missense mutations may be critical ...

Schüchner(Stefan),Tembe(Varsha),Rodriguez(... J Biol Chem 2005-04-19

...BRCA1, but the only known BRCA1-independent BARD1 function is a p53-dependent proapoptotic activity stimulated by nuclea...

Coupier(Isabelle),Gauthier-Villars(Marion)... Rev Prat 2005-02-22

...BRCA1 and BRCA2 genes are involved in familial breast and (or) ovarian cancer. Mutations of these two genes could explai...

Lorenzo Bermejo(J),Hemminki(K) Ann Oncol 2005-07-12

The prevalence of families eligible for BRCA1/2 mutation testing in the population burden of breast cancer was analysed ...

Hughes(David J),Ginolhac(Sophie M),Coupier... Cancer Epidemiol Biomarkers... 2005-04-20

...BRCA1 mutation carriers. The study includes 778 women carrying a BRCA1 germ-line mutation belonging to 403 families. The...

McClain(Monica R),Palomaki(Glenn E),Nathan... Genet Med 2005-09-01

Mutations in BRCA1 or BRCA2 genes increase breast cancer risk. Assuring reliability of information about these mutations...

McClain(Monica R),Nathanson(Katherine L),P... Genet Med 2005-09-01

Three founder mutations in BRCA1 or BRCA2 genes increase breast cancer risk among Ashkenazi Jewish women. Reported estim...

Andersen(J L),Zimmerman(E S),DeHart(J L),M... Cell Death Differ 2005-09-07

...BRCA1), a known target of ATR, is activated in the presence of Vpr. In addition, the gene encoding the growth arrest and...

Chunder(Neelanjana),Roy(Anup),Roychoudhury... Pathol Res Pract 2005-05-03

...BRCA1, BRCA2, BRCAX, ATM, TP53, and RB1. Although a few cases were studied, our findings suggest that in at least a prop...

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