Since the gene encoding BRCA1 was first cloned in 1994, researchers have sought to establish the molecular basis for its...
...BRCA1 and BRCA2, which account for a sizeable fraction of the clearly inherited forms of breast cancer occurring in auto...
...BRCA1 and BRCA2 mutation status, ER status, and patient prognosis. Beyond its impact on research into the basic mechanis...
Due to the complexity of information surrounding BRCA1/2 counseling and testing and its time consuming nature, efforts t...
...BRCA1 tumor suppressor. Examination of Chk2 protein revealed a decreased expression of Chk2 protein in cisplatin-resista...
...BRCA1-mutated breast cancer cells. The extent to which 4-HPR induced apoptosis in BRCA1-mutated cells correlated with th...
...BRCA1 class with a probability >80% had an aberrant methylation of the BRCA1 promoter. This fact suggests that somatic B...
...BRCA1, BRCA2, ATM, TP53, RB1, MAD2, BUB1, APC and beta-actin) in oocytes and embryos. A full characterization of all gen...
...BRCA1 and four in BRCA2 and four unclassified variants (UV). We also identified the presence of the BRCA1 3889_3890delG ...
BRCA1 gene mutations account for nearly all families with multiple cases of both early onset breast and/or ovarian cance...
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