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TP53 BRCA1 CRISPR single-cell cancer

Reini(Kaarina),Uitto(Lahja),Perera(David),... Chromosoma 2005-01-07

...BRCA1 and p53. Spindle checkpoint activation does not affect this centrosomal localisation. Moreover, in the testis, we ...

Hill(David A),de la Serna(Ivana L),Veal(Ti... J Cell Biochem 2005-03-07

BRCA1 is a tumor suppressor gene linked to familial breast and ovarian cancer. The BRCA1 protein has been implicated in ...

Marroni(Fabio),Aretini(Paolo),D'Andrea(Emm... Eur J Hum Genet 2005-05-11

Accurate estimates of breast and ovarian cancer penetrance in BRCA1/2 mutation carriers are crucial in genetic counselin...

Taron(Miquel),Rosell(Rafael),Felip(Enrique... Hum Mol Genet 2005-04-25

...BRCA1 plays a central role in DNA repair, and decreased BRCA1 mRNA expression in the human breast cancer HCC1937 cell li...

Rogozińska-Szczepka(J),Utracka-Hutka(B),Gr... Ann Oncol 2005-03-21

Incidence of primary bilateral breast cancer (BC) is rare and does not exceed 5%. BRCA1/2 mutation carriers diagnosed wi...

BRCA1 and transcription.

Lane(Timothy F) Cancer Biol Ther 2005-05-19

...BRCA1 tumor suppressor gene is expressed in all mammalian cells. Within these cells, the BRCA1 protein product interacts...

Couch(Fergus J) Cancer Biol Ther 2005-05-19

...BRCA1 gene 10 years ago much has been learned about the role of the BRCA1 protein in cancer development. In particular, ...

Szabo(Csilla I),Worley(Terri),Monteiro(Alv... Cancer Biol Ther 2005-05-19

Germ-line mutations in BRCA1 account for the majority of familial breast and ovarian cancer cases and development of can...

Botuyan(Maria Victoria E),Nominé(Yves),Yu(... Structure 2005-02-09

...BRCA1 function in DNA damage-induced checkpoint control. Our NMR data also reveal a dynamic interaction between BRCA1-BR...

Seo(Jae Hong),Cho(Dae-Yeon),Ahn(Se-Hyun),Y... Hum Mutat 2005-03-31

...BRCA1 c.5445G>A and BRCA2 c.2259delT) are novel. The total prevalence of germline pathogenic mutations in BRCA1 and/or B...

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