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Prophylactic mastectomy: indications, options, and reconstructive alternative...

Spear(Scott L),Carter(Mary Ella),Schwarz(K... Plast Reconstr Surg 2005-11-10

...BRCA1 and BRCA2 have become increasingly important in determining risk; a BRCA1-positive patient's risk of developing br...

Pressure overload and neurohumoral activation differentially affect the myoca...

Schott(Peter),Singer(Silke S),Kögler(Haral... Proteomics 2005-09-30

...BRCA1) that is involved in myocardial hypertrophy. Furthermore, we demonstrate that increased afterload-induced hypertro...

Oral contraceptive use and risk of early-onset breast cancer in carriers and ...

Milne(Roger L),Knight(Julia A),John(Esther... Cancer Epidemiol Biomarkers... 2005-06-02

...BRCA1 or BRCA2 are unclear.,Subjects were population-based samples of Caucasian women that comprised 1,156 incident case...

Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and u...

Chen(Ceshi),Sun(Xiaodong),Ran(Qimei),Wilki... Oncogene 2005-05-31

...BRCA1, HIF-1alpha, etc. The Kruppel-like factor 5 (KLF5) transcription factor regulates biological processes involved in...

Complete mutation screening and haplotype characterization of the BRCA1 gene ...

Frost(Petter),Jugessur(Astanand),Apold(Jar... Dis Markers 2005-08-18

...BRCA1. A highly sensitive method (REF-SSCP) was applied to screen the open reading frame and the 5'UTRs of BRCA1 for mut...

BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation.

Yan(Ying),Spieker(Rebecca S),Kim(Min),Stoe... Oncogene 2005-05-31

...BRCA1-mediated G2/M checkpoint response. In this study, we assessed the role of ERK1/2 kinases in the regulation of BRCA...

Identification of germline BRCA1 and BRCA2 genetic alterations in Greek breas...

Kataki(A),Gomatos(Ip),Pararas(N),Armakolas... Clin Genet 2005-06-16

...BRCA1 missense mutations, one novel BRCA1 intronic deletion, three novel (previously reported) BRCA2 truncating mutation...

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tu...

van Beers(Erik H),van Welsem(Tibor),Wessel... Cancer Res 2005-03-14

...BRCA1 and controls, followed by BRCA1 compared with BRCA2, suggesting different tumor development pathways for BRCA1 and...

A predictor based on the somatic genomic changes of the BRCA1/BRCA2 breast ca...

Alvarez(Sara),Diaz-Uriarte(Ramon),Osorio(A... Clin Cancer Res 2005-05-31

...BRCA1 class with a probability >80% had an aberrant methylation of the BRCA1 promoter. This fact suggests that somatic B...

Second primary malignancies in patients with male breast cancer.

Hemminki(K),Scélo(G),Boffetta(P),Mellemkja... Br J Cancer 2005-05-26

...BRCA1) mutations may explain the findings for pancreatic and prostate cancers. Increases at other sites may be related t...

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