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TP53 BRCA1 CRISPR single-cell cancer

Bridge(Wendy L),Vandenberg(Cassandra J),Fr... Nat Genet 2005-09-29

...BRCA1 (refs. 1-6) and has an important role in BRCA1-dependent DNA repair and checkpoint functions. We cloned the chicke...

Meetei(Amom Ruhikanta),Medhurst(Annette L)... Nat Genet 2005-09-29

...BRCA1 and BRCA2 (refs. 2,3). We previously purified a Fanconi anemia core complex containing the FANCL ubiquitin ligase ...

Levran(Orna),Attwooll(Claire),Henry(Rashid... Nat Genet 2005-09-29

...BRCA1-containing nuclear foci. Cells from individuals with Fanconi anemia of complementation groups D1 and J (FA-D1 and ...

Halbert(Ch),Kessler(L),Collier(A),Paul Wil... Clin Genet 2005-10-21

...BRCA1/2 mutations. Overall, respondents reported moderate levels of cancer-specific distress. Younger age (coefficient=6...

Cruger(D G),Kruse(T A),Gerdes(A M) Clin Genet 2005-10-21

We report an approach for BRCA1/2 testing whereby genetic testing can be offered to families at high risk of hereditary ...

Freedman(Matthew L),Penney(Kathryn L),Stra... Cancer Res 2005-10-27

Rare, highly penetrant germ line mutations in BRCA1 strongly predispose women to a familial form of breast and ovarian c...

Prat(Jaime),Ribé(Adriana),Gallardo(Alberto... Hum Pathol 2005-10-12

...BRCA1 and BRCA2 tumor suppressor genes, whereas HNPCC is associated with germ line mutations in the DNA mismatch repair ...

Spinka(Christine),Carroll(Raymond J),Chatt... Genet Epidemiol 2005-12-06

...BRCA1/2 mutations and reproductive risk factors in the etiology of ovarian cancer.

Kasprzak(Lidia),Mesurolle(Benoit),Tremblay... World J Surg Oncol 2005-10-14

...BRCA1-positive patient has been reported in the literature and none in BRCA2-positive individuals.,Careful documentation...

Henderson(Beric R) Bioessays 2005-11-15

The subcellular location and function of many proteins are regulated by nuclear-cytoplasmic shuttling. BRCA1 and BARD1 p...

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