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TP53 BRCA1 CRISPR single-cell cancer

Kleiman(Frida E),Wu-Baer(Foon),Fonseca(Dan... Genes Dev 2005-06-20

...BRCA1/BARD1 ubiquitin ligase activity. Significantly, siRNA-mediated knockdown of BRCA1 and BARD1 resulted in stabilizat...

Al-Wahiby(S),Slijepcevic(P) Cytogenet Genome Res 2005-07-12

...BRCA1 mutation. Finally, we analyzed mouse embryonic stem cells lacking functional Brca1 and observed the presence of te...

Hartmann(Carolin),John(Anika L),Klaes(Rüdi... Hum Mutat 2005-10-24

We have tested for large BRCA1 gene rearrangements in German high-risk breast and ovarian cancer families previously scr...

Xu(Xiao-Li),Yu(Jian),Zhang(Hong-Yu),Sun(Me... World J Gastroenterol 2005-01-05

...BRCA1), cadherin 1, type 1, E-cadherin (epithelial) (CDH1), death-associated protein kinase 1 (DAPK1), DNA (cytosine-5-)...

Starita(Lea M),Horwitz(Andrew A),Keogh(Mic... J Biol Chem 2005-08-16

...BRCA1/BARD1. Overexpression of BRCA1 in cells stimulated the DNA damage-induced ubiquitination of Rpb1. Similar to the i...

Ingvarsson(Sigurdur) Drugs Today (Barc) 2005-10-20

...BRCA1 and BRCA2, in which DNA repair function is interrupted, account for the majority of familial breast cancers. The m...

Shen(Dejun),He(Jianbo),Chang(Helena R) Int J Mol Med 2005-08-08

...BRCA1 and p53, tissue-specific genes CEA and PSA and two breast cancer-related genes Her2/neu and MUC1. We found a high ...

Kalnina(Zane),Zayakin(Pawel),Silina(Karīna... Genes Chromosomes Cancer 2005-04-12

...BRCA1 and APC). Splicing defects can arise from inherited or somatic mutations in cis-acting regulatory elements (splice...

Hartman(Anne-Renée) Recent Results Cancer Res 2005-02-10

...BRCA1 and 2 account for greater than 60% of inherited breast cancer. Mutations in additional undiscovered high and low p...

Muti(Paola) Recent Results Cancer Res 2005-02-10

...BRCA1 and BRCA2 susceptibility genes, familial history of breast cancer, age, higher socioeconomic status, ionizing radi...

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