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TP53 BRCA1 CRISPR single-cell cancer

Monteiro(A N),Humphrey(J S) Breast Dis 2005-03-21

...BRCA1 account for the majority of families with breast and ovarian cancer predisposition. BRCA1 encodes a 1,863 amino ac...

Struewing(J P) Breast Dis 2005-03-21

A restricted number of mutant BRCA1 alleles are present at high frequency in the Ashkenazi Jewish population: 185delAG a...

Rimer(B K),Sugarman(J),Winer(E),Bluman(L G... Breast Dis 2005-03-21

While the cloning of BRCA1 and BRCA2 in 1994 and 1995 engendered great enthusiasm from cancer patients, their families a...

Berry(D A),Parmigiani(G) Breast Dis 2005-03-21

Tests for the presence of mutations of genes BRCA1 and BRCA2 are increasingly available. Genetic testing creates dilemma...

Dressler(L) Breast Dis 2005-03-21

...BRCA1 gene is available commercially and clinically. The information gained from this test impacts not only on the indiv...

MacLennan(Susan E) Breast Dis 2005-03-21

...BRCA1 and BRCA2 gene mutations and their implications for breast cancer risk have led to renewed interest in prophylacti...

Trauernicht(Amy M),Boyer(Thomas G) Breast Dis 2005-03-21

Since the gene encoding BRCA1 was first cloned in 1994, researchers have sought to establish the molecular basis for its...

Struewing(Jeffery P) Breast Dis 2005-03-21

...BRCA1 and BRCA2, which account for a sizeable fraction of the clearly inherited forms of breast cancer occurring in auto...

Meltzer(Paul S) Breast Dis 2005-03-21

...BRCA1 and BRCA2 mutation status, ER status, and patient prognosis. Beyond its impact on research into the basic mechanis...

Stanisławska-Sachadyn(Anna),Paszko(Zygmunt... Mutat Res 2005-03-24

...BRCA1, BRCA2 and NBS1 genes. The approach appears to be promising in screening for unknown point mutations.

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