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[Molecular targeted therapy for progressive low-grade gliomas in children].

Sun(YL),Li(M),Liu(JJ),Gao(WC),Wu(YF),Wan(LL)… Zhongguo Dang Dai Er Ke Za Zhi 2025-06-15

...NF1 mutation receiving everolimus for 21 months, discontinued treatment due to sustained disease stability. No severe ad...

Effect of nutritional state and dispersal on the reproductive efficiency in Tri…

Lobbia(PA),Rodríguez(C),Mougabure-Cueto(G) Acta Trop 2019-03-00

...NF1. The experimental arena was 10 m long and contained two shelters. Groups of 30 virgin females of each NF were releas...

Multigene Sequencing Analysis of Children Born Small for Gestational Age With I…

Freire(BL),Homma(TK),Funari(MFA),Lerario(AM)… J Clin Endocrinol Metab 2019-00-01

...NF1 (n = 1). None of these patients had clinical findings that allowed for a clinical diagnosis. Seven patients were SGA...

Lorlatinib Treatment Elicits Multiple On- and Off-Target Mechanisms of Resistan…

Redaelli(S),Ceccon(M),Zappa(M),Sharma(GG),Ma… Cancer Res 2018-00-15

...NF1 mutation and hyperactivation of EGFR and ErbB4. These data provide an extensive characterization of resistance mecha...

Current prospects of hereditary adrenal tumors: towards better clinical managem…

Ohmoto(A),Hayashi(N),Takahashi(S),Ueki(A) Hered Cancer Clin Pract 2024-03-26

...NF1, and VHL have been identified, universal multi-gene germline panel testing is warranted as a comprehensive and cost-...

Clinical and genetic characteristics of BAP1-mutated non-uveal and uveal melano…

Matull(J),Placke(JM),Lodde(G),Zaremba(A),Uti… Front Immunol 2024-00-00

...NF1, BRAF V600 and NRAS Q61 mutations occurring in decreasing frequency, consistent with a strong UV association. Surviv...

Identifying Diffuse Glioma Subtypes Based on Pathway Enrichment Evaluation.

Feng(Q),Dong(Z),Nie(R),Wang(X) Interdiscip Sci 2024-09-00

...NF1 and MUC16 mutation rates, while high enrichment of neurons and nervous system pathways, and high tumor purity, estro...

Whole-exome sequencing has revealed novel genetic characteristics in intracrani…

Huang(X),Huang(J),Zhou(X),Zhang(C),Ding(X),W… Histopathology 2024-06-00

...NF1 mutation was associated with shorter overall survival and progression-free survival in IGCT patients. Clonal evoluti...

Genome-Wide Sequencing Reveals MicroRNAs Downregulated in Cerebral Cavernous Ma…

Kar(S),Bali(KK),Baisantry(A),Geffers(R),Sami… J Mol Neurosci 2017-02-00

...NF1, and ENG, which are previously characterized as key regulators of CCM pathology. To date, this is the first study to...

Comprehensive genomic profiling of malignant phyllodes tumors of the breast.

Nozad(S),Sheehan(CE),Gay(LM),Elvin(JA),Vergi… Breast Cancer Res Treat 2017-00-00

...NF1 (45.8%), MED12 (45.8%), CDKN2A/B (33.3%), and MLL2 (33.3%). Targetable kinase fusions including KIAA1549-BRAF or FGF...

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