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Analysis of large mutations in BARD1 in patients with breast and/or ovarian c...

Klonowska(Katarzyna),Ratajska(Magdalena),C... Sci Rep 2016-03-28

...BARD1. Although it was suggested that large mutations may contribute substantially to the deleterious variants of BARD1,...

BARD1 mediates TGF-β signaling in pulmonary fibrosis.

André(Pierre-Alain),Prêle(Cecilia M),Vierk... Respir Res 2016-07-11

...BARD1 and BARD1β in fibrotic tissues.,Our data suggest that FL BARD1 and BARD1β might be mediators of pleiotropic effect...

BRCA1 and BARD1 colocalize mainly in the cytoplasm of breast cancer tumors, a...

Wiener(David),Gajardo-Meneses(Patricia),Or... Breast Cancer Res Treat 2016-07-11

...BARD1-α and BARD1-β. BRCA1 and BARD1 expressions were performed by immunohistochemistry and immunofluorescence in 103 br...

Interaction of BARD1 and HP1 Is Required for BRCA1 Retention at Sites of DNA ...

Wu(Wenwen),Nishikawa(Hiroyuki),Fukuda(Taka... Cancer Res 2016-01-23

...BARD1 is crucial for its retention through interaction with HP1. In response to DNA damage, BARD1 interacts with Lys9-di...

Functional variant analyses (FVAs) predict pathogenicity in the BRCA1 DNA dou...

Loke(Johnny),Pearlman(Alexander),Upadhyay(... Hum Mol Genet 2016-02-16

...BARD1, PALB2, BRCA2 and FANCD2, phosphorylation of p53 or BRCA1 nuclear localization in response to DNA damage caused by...

Cancer predisposing BARD1 mutations affect exon skipping and are associated w...

Ratajska(Magdalena),Matusiak(Magdalena),Ku... Oncol Rep 2016-08-08

...BARD1 are highly upregulated and correlated with poor outcome. Recent data indicate that germline mutations of BARD1 may...

Functional Analysis of BARD1 Missense Variants in Homology-Directed Repair of...

Lee(Cindy),Banerjee(Tapahsama),Gillespie(J... Hum Mutat 2016-08-19

...BARD1 domains, residues crucial for HDR were located in the N- and C- termini of BARD1. In the BARD1 RING domain, critic...

An asbestos-exposed family with multiple cases of pleural malignant mesotheli...

Cheung(Mitchell),Kadariya(Yuwaraj),Pei(Jia... Cancer Genet 2016-01-05

...BARD1, also revealed no mutation. DNA microarray analysis of tissue from two mesotheliomas revealed multiple genomic imb...

Targeted massively parallel sequencing of a panel of putative breast cancer s...

Li(Jun),Meeks(Huong),Feng(Bing-Jian),Heale... J Med Genet 2016-10-12

...BARD1, BRIP1, MRE11, NBN, RAD50, RAD51C, RAD51D and CDK4). The relevant variants were then genotyped in 558 family membe...

Genetic characterization of early onset ovarian carcinoma.

Bernards(Sarah S),Norquist(Barbara M),Harr... Gynecol Oncol 2016-06-01

...BARD1, BRCA1, BRCA2, BRIP1, MLH1, MSH2, MSH6, PALB2, PMS2, RAD51D, and RAD51C) and additional candidate genes in DNA rep...

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