Mutations in DNA mismatch repair (MMR) pathway genes (MSH2, MSH6, MLH1, and PMS2) are linked to acquired resistance to t...
...MSH2, MPG, and XPA. Among all modifications analyzed, H3K18ac exhibited the most pronounced decline, suggesting its pref...
...Msh2), which is responsible for correcting base-base mismatches and insertion/deletion loops during cell proliferation. ...
...MSH2 promoter methylation was occasionally associated with reduced MSH2 expression. Global loss of MSH6 (score 0), defin...
...MSH2 and MEN1 factor Menin variants in combination with DNA mismatch repair factor MSH6 and transcription factor JUND, r...
...MSH2, MSH6, p53, E-cadherin) and chromosomal in situ hybridization (EBER): EBV positive tumors (EBV+), tumors with micro...
...MSH2, LIG4). We further measured expressions of DNA methyltransferase DNMT1 and demethylase TET2, and methylation of the...
...MSH2 was the most common germline change (36%). Of those tested for loss of heterozygosity (LOH) or microsatellite insta...
...MSH2 in nondrinkers (p = 0.039), and PMS2 was lower in advanced-stage patients (p = 0.023). Immunologically, MSH2 expres...
...MSH2 expression, one of these with concurrent dubious loss of MSH6 on the TMA. However, MSH2 and MSH6 expression was ret...
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