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Repair of 2 um Plasmid DNA in Saccharomyces cerevisiae.

McCready(S J),Cox(B S) Curr Genet 2013-11-06

...rad1 (excision-defective) mutant 81% of plasmid molecules still had dimers after 3 h, suggesting that excision repair op...

Role of Saw1 in Rad1/Rad10 complex assembly at recombination intermediates in b…

Li(Fuyang),Dong(Junachao),Eichmiller(Robin),… EMBO J 2013-04-02

...Rad1/Rad10 in a purified system in vitro. Our results allow us to formulate a model of Rad1/Rad10/Saw1 nuclease complex ...

Lagging strand maturation factor Dna2 is a component of the replication checkpo…

Kumar(Sandeep),Burgers(Peter M) Genes Dev 2013-03-22

...Rad17 and human Rad9-Rad1-Hus1) and Dpb11, the ortholog of human TopBP1. A triple mutant that eliminates the checkpoint ...

A role for Myh1 in DNA repair after treatment with strand-breaking and crosslin…

Jansson(Kristina),Alao(John P),Viktorsson(Kr… Environ Mol Mutagen 2013-08-13

...rad1 mutant background. Exposure of cells to cisplatin leads to a moderate overall accumulation of Myh1 protein. Interes...

A mechanism of gene amplification driven by small DNA fragments.

Mukherjee(Kuntal),Storici(Francesca) PLoS Genet 2013-05-09

...Rad1, Rad10, and Pol32, and independent of Rad51, suggesting a single-strand annealing mechanism. Our results reveal a n...

A microarray analysis of gene expression patterns during early phases of newt l…

Sousounis(Konstantinos),Michel(Christian S),… Mol Vis 2013-09-06

...rad1 and vascular endothelial growth factor receptor 1 showed upregulation for the dorsal iris 3 and 5 days post- lentec...

Conditional inactivation of the DNA damage response gene Hus1 in mouse testis r…

Lyndaker(Amy M),Lim(Pei Xin),Mleczko(Joanna … PLoS Genet 2013-06-13

...RAD1 had a broader distribution that only partially overlapped with RAD9, and localization of both RAD1 and the ATR acti...

A role for the MRN complex in ATR activation via TOPBP1 recruitment.

Duursma(Anja M),Driscoll(Robert),Elias(Josh … Mol Cell 2013-06-10

...RAD1-HUS1) complex is not required for TOPBP1 recruitment but is essential for TOPBP1 function. Thus, whereas MRN is req...

The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk…

Lee(Joon),Dunphy(William G) Mol Biol Cell 2013-11-14

...Rad17, the Rad9-Hus1-Rad1 (9-1-1) complex, and Claspin. We have observed that egg extracts lacking the Mre11-Rad50-Nbs1 ...

Understanding the role of the Q338H MUTYH variant in oxidative damage repair.

Turco(Eleonora),Ventura(Ilenia),Minoprio(Ann… Nucleic Acids Res 2013-06-19

...RAD1:HUS1 (9-1-1) complex. In comparison with Mutyh(-)(/)(-) mouse embryo fibroblasts expressing a wild-type MUTYH cDNA,...

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