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Drosophila Yemanuclein associates with the cohesin and synaptonemal complexes.

Meyer(Régis E),Algazeery(Ahmed),Capri(Michèl… J Cell Sci 2015-09-01

...Spo11 homolog mei-W68, modified a yem(1) dominant effect on crossover distribution, suggesting that Yem has an early rol...

Mechanism and regulation of meiotic recombination initiation.

Lam(Isabel),Keeney(Scott) Cold Spring Harb Perspect Biol 2015-09-11

...Spo11 protein. This review summarizes recent studies pertaining to the formation of meiotic DSBs, including the mechanis...

Study of single nucleotide polymorphism (rs28368082) in SPO11 gene and its asso…

Ghalkhani(Esmat),Sheidai(Masoud),Gourabi(Ham… J Assist Reprod Genet 2015-05-27

The present study is a case-control analysis of a SNP (rs28368082) in exon 7 of the SPO11 gene and its possible associat...

Synaptonemal complex extension from clustered telomeres mediates full-length ch…

Xiang(Youbin),Miller(Danny E),Ross(Eric J),S… Proc Natl Acad Sci U S A 2015-04-28

...SPO11, and RAD51, a key player in homologous recombination, we confirmed that SC formation begins near the telomeres and...

UV and genotoxic stress induce ATR relocalization in mouse spermatocytes.

Di Siena(Sara),Campolo(Federica),Rossi(Pelle… Int J Dev Biol 2014-01-23

...SPO11 topoisomerase. ATM is the kinase which mediates the formation of phosphorylated H2AX (H2AX) meiotic foci, while A...

Molecular determinants of sporulation in Ashbya gossypii.

Wasserstrom(Lisa),Lengeler(Klaus B),Walther(… Genetics 2014-03-25

...Spo11 is apparently not required for sporulation; however, the absence of DMC1, which repairs DSBs in S. cerevisiae, res...

Initiation of meiotic recombination in Ustilago maydis.

Kojic(Milorad),Sutherland(Jeanette H),Pérez-… Genetics 2014-07-06

...spo11Δ cross were still able to germinate but the process was highly disturbed and the meiotic products were imbalanced ...

Initiation of meiotic recombination: how and where? Conservation and specificit…

de Massy(Bernard) Annu Rev Genet 2014-04-14

...SPO11 protein, assisted by several other factors. Some of them are absolutely required, whereas others are needed only f...

Identification of DSB-1, a protein required for initiation of meiotic recombina…

Stamper(Ericca L),Rodenbusch(Stacia E),Rosu(… PLoS Genet 2014-03-21

...Spo11 enzyme; however, the activity of Spo11 is regulated by additional factors that are poorly conserved through evolut...

A mutation in the FHA domain of Coprinus cinereus Nbs1 Leads to Spo11-independe…

Crown(K Nicole),Savytskyy(Oleksandr P),Malik… G3 (Bethesda) 2014-06-09

...Spo11-dependent DSBs during prophase. We propose that replication-dependent DSBs, resulting from defective replication f...

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