...BRCA1 or BRCA2 genes were found in 16 (8%) patients, and BRCA1 pathogenic mutations were found in 18 (9%) patients. No p...
...BRCA1/2 mutations by denaturing high-performance liquid chromatography and DNA sequencing.,Three deleterious germline BR...
Women carrying one mutated BRCA1 allele are at increased risk of developing breast and ovarian cancer but tumor initiati...
...BRCA1 cancer predisposing mutation was described among patients with Uterine Serous Papillary Carcinoma (USPC). A BRCA2 ...
...BRCA1 and BRCA2 genes and is associated with an 11-40% risk of developing ovarian cancer. The hereditary nonpolyposis co...
...BRCA1/2 testing and prophylactic surgery among BRCA1 and BRCA2 mutation carriers. They highlight the role of patient pre...
...BRCA1 coding region and a panel of 94 unrelated family breast cancer risk consultands previously screened in a clinical ...
...BRCA1) revealed two evolutionarily conserved noncoding sequences (CNS) in intron 2, 5 kb downstream of the core BRCA1 pr...
...BRCA1-associated tumors, but only one of 15 BRCA2-associated tumors was positive for CK5/14. In contrast to sporadic CK5...
...Brca1, another defect that confers radiosensitivity. Similarly, these cells showed accelerated telomere shortening and m...
山东省济南市章丘区文博路2号
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