...BRCA1/2 mutation carriers, although these results are based on small numbers. CONCLUSION These analyses suggest that the...
...Brca1 C-terminal domain, were at least 10-fold less active in restoring gap filling to the immunodepleted extracts, and ...
...BRCA1 COOH-terminal (BRCT) domains are protein modules found in many proteins that regulate DNA damage responses (Koonin...
...BRCA1 allele may serve as the second hit in a patient with a diploid locus and missense mutation on the other allele.
...BRCA1 or BRCA2 (BRCA1/2) gene alteration. Subjects were 28 high-risk women who self-referred to a genetic counseling and...
...BRCA1.,The response to radiation of cells with mutations in ATM or BRCA1 was examined, as were BRCA1-mutant tumour cells...
...BRCA1 breast cancer gene) are investigated.
...BRCA1/2 mutations in the absence of breast cancer, based on data from the Washington Ashkenazi Kin-Cohort Study. We also...
...BRCA1) as very likely biological binding sites of Chk2FHA. The results provide useful leads for further biological analy...
...BRCA1 LOH was an independent prognostic factor in stages I and II (p=0.001).,BRCA1 LOH is a molecular alteration present...
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