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TP53 BRCA1 CRISPR single-cell cancer

Buecher(B),Warcoin(M),Rolland(E),Abdullazo... Eur J Hum Genet 2026-01-29

...BRCA1, BRCA2, CDKN2A, MLH1, MSH2, MSH6, PALB2, PMS2, RAD51C, RAD51D, STK11) was performed in 496 patients with pancreati...

Michaelson-Cohen(R),Armon(S),Srebnik(N),Vo... Isr J Health Policy Res 2026-01-30

BACKGROUND: The implementation of Israeli National screening for BRCA1/BRCA2 pathogenic variants (PVs) in 2020 has led t...

Chen(K),Zhang(Y),Ruan(H),Wei(Z),Wang(K),Ca... Autophagy 2026-05-00

...BRCA1: BRCA1 DNA repair associated; Cas: CRISPR-associated; CCCP: carbonyl cyanide m-chlorophenyl hydrazone; ccRCC: clea...

Dore(S),Sacchi(M),Pinna(A),Palmieri(G),Pal... Oncol Res None

...BRCA1 associated deubiquitinase 1 (BAP1), splicing factor 3b subunit 1 (SF3B1), and eukaryotic translation initiation fa...

Chudziak(AV),Morris(TJ),Maliy(D),Saglimben... Curr Issues Mol Biol 2026-01-16

...BRCA1, and STAT5B, underscoring the need for diverse representation in TC genomics. Notably, MTOR mutations were signifi...

Liu(Q),Fan(Y),Huang(C),Wu(M),Jin(Y),Tao(L)... ESMO Open 2026-02-00

...BRCA1/2-mutated epithelial ovarian cancer patients between 2015 and 2024. Patients who achieved complete or partial resp...

Rossouw(B),Araujo(M),Krause(A),Baine-Savan... Fam Cancer 2026-01-31

...BRCA1 and BRCA2 variants accounting for 20–55% of these cases, while other implicated genes include BRIP1, ATM, RAD51C, ...

Kang(DY),Chi(WJ),Cho(J),Jang(KJ) Sci Rep 2026-01-07

...BRCA1, and p53 and normalized cell cycle regulation by modulating the expression of CDK4, Cyclin D1/E, and p21/p27. Cell...

Darnold(JS),Jonkers(J) Nat Genet 2026-07-00

...BRCA1 and BRCA2 (hereafter referred to as BRCA1/2) hereditary breast and ovarian cancer genes three decades ago, genetic...

Arora(M),Yaseen(YS),Mahmood(AAR),Sangi(SMA... BMC Pharmacol Toxicol 2026-01-06

...BRCA1-associated tumor progression is involved.

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