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TP53 BRCA1 CRISPR single-cell cancer

Altaha(Ramin),Reed(Eddie),Abraham(Jame) W V Med J 2004-03-08

...BRCA1 and BRCA2 mutations (BRCA1/2 mutation) have a 65% to 85% cumulative lifetime risk of developing invasive breast ca...

Liede(Alexander),Karlan(Beth Y),Narod(Stev... J Clin Oncol 2004-03-02

...BRCA1 or BRCA2, with a focus on the cancer sites most relevant to men. Male BRCA1 mutation carriers are at increased ris...

Wang(Wensheng),Seki(Masayuki),Otsuki(Makot... Biochim Biophys Acta 2004-04-23

...BRCA1-associated genome surveillance complex (BASC), a supercomplex possibly involved in the recognition and repair of a...

Fujiuchi(Nobuko),Aglipay(Jason A),Ohtsuka(... J Biol Chem 2004-06-15

...BRCA1-mediated apoptosis and inflammation signaling pathways. Here we report that most breast cancer cell lines examined...

Ouchi(Mutsuko),Fujiuchi(Nobuko),Sasai(Kaor... J Biol Chem 2004-06-15

...BRCA1 breast cancer tumor suppressor also localizes to the centrosome and that BRCA1 inactivation results in loss of the...

Wong(Alice S T),Auersperg(Nelly) Reprod Biol Endocrinol 2004-09-08

...BRCA1 and BRCA2, provide a background to facilitate understanding of the early changes in ovarian carcinogenesis. This o...

Nakajima(Akinori),Kataoka(Ken),Hong(Mei),S... Cancer Lett 2004-01-05

...BRCA1. We cloned mouse BRAP2 cDNA and showed the presence of isoforms.

Nishikawa(Hiroyuki),Ooka(Seido),Sato(Ko),A... J Biol Chem 2004-04-01

...BRCA1 as a tumor suppressor, the biochemical consequence of the activity is not yet known. Here we report that BRCA1-BAR...

Fiszer-Maliszewska(Łucja),Kazanowska(Berna... J Appl Genet 2004-01-30

...BRCA1 [hereditary breast (ovarian) cancer, HB(O)C] or a complex consistent with both LFL and HB(O)C. Children with leuke...

Dong(Yuanshu),Hakimi(Mohamed-Ali),Chen(Xia... Mol Cell 2004-01-05

...BRCA1/BARD1/BRCC45/BRCC36 revealed an enhanced E3 ligase activity compared to that of BRCA1/BARD1 heterodimer. In vivo, ...

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