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TP53 BRCA1 CRISPR single-cell cancer

Mirkovic(Nebojsa),Marti-Renom(Marc A),Webe... Cancer Res 2004-07-26

The BRCA1 gene from individuals at risk of breast and ovarian cancers can be screened for the presence of mutations. How...

Beger(Carmela),Ramadani(Marco),Meyer(Steph... Clin Cancer Res 2004-12-27

...BRCA1-regular as compared with BRCA1-reduced or BRCA1-absent tumors. In contrast, no substantial differences in BRCA2 ex...

Evans(D G R),Eccles(D M),Rahman(N),Young(K... J Med Genet 2004-09-27

To develop a simple scoring system for the likelihood of identifying a BRCA1 or BRCA2 mutation.,DNA samples from affecte...

Desper(Richard),Khan(Javed),Schäffer(Aleja... J Theor Biol 2004-09-27

...BRCA1 mutations from those with BRCA2 mutations, with sporadic tumors separated from both groups and from each other. We...

Kitagawa(Risa),Bakkenist(Christopher J),Mc... Genes Dev 2004-07-19

...BRCA1 are required for the recruitment of previously activated ATM to the sites of DNA breaks after ionizing irradiation...

Hausmann(Stéphane),Schwer(Beate),Shuman(St... Biochemistry 2004-08-11

...BRCA1 carboxyl terminus (BRCT) domain but lacks the large N- and C-terminal domains found in fungal and metazoan Fcp1 en...

Chee(Y C) Ann Acad Med Singapore 2004-09-17

...BRCA1 and BRCA2, were found to confer high risks of breast and ovarian cancer on women with these genes. The application...

Rodríguez-López(Raquel),Osorio(Ana),Ribas(... Int J Cancer 2004-07-16

...BRCA1/2 genes, with a frequency of 5.74% (n = 174) compared to a control population (n = 567) and another subset of brea...

Johannsdottir(Hrefna K),Johannesdottir(Gud... Anticancer Res 2004-12-10

Chromosomal aberrations in breast tumors from BRCA1 and BRCA2 germ-line mutation carriers are considerably more frequent...

de Candia(Paola),Benera(Robert),Solit(Davi... Adv Cancer Res 2004-12-29

...BRCA1 expression and may be involved in hormone-dependent regulation of BRCA1 homeostasis. Thus, all four members of the...

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