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TP53 BRCA1 CRISPR single-cell cancer

Jefford(Charles Edward),Feki(Anis),Harb(Je... Oncogene 2004-06-01

...BRCA1 heterodimer and induction of apoptosis in a BRCA1-independent manner. We have constructed a series of BARD1 deleti...

McPherson(John Peter),Lemmers(Bénédicte),H... Genes Dev 2004-06-17

...Brca1 results in cellular demise or tumorigenesis depending on cellular context. Inactivation of p53 contributes to Brca...

Menkiszak(Janusz),Brzosko(Marek),Górski(Bo... J Appl Genet 2004-06-29

The study aimed to determine whether hereditary ovarian cancers that are not caused by BRCA1/BRCA2 constitutional mutati...

Gal(Inbar),Gershoni Baruch(Ruth),Haber(Dan... Fam Cancer 2004-07-22

...BRCA1 and BRCA2 in high-risk non-Ashkenazi Jews. In a Libyan family the 1100delAT BRCA1 mutation was detected and the 87...

Muller(Danièle),Bonaiti-Pellié(Catherine),... Fam Cancer 2004-07-22

...BRCA1 gene, using combined DGGE and direct sequencing. For haplotype analysis, six polymorphic markers were used for all...

Reichelt(Jon G),Heimdal(Ketil),Møller(Pål)... Fam Cancer 2004-07-22

To examine the short-term psychological impact of receiving definite results concerning BRCA1 mutation status in a clini...

Murday(Victoria),Pears(R),Ball(J),Eeles(R)... Fam Cancer 2004-07-22

...BRCA1 or -2 mutation, but it is important to screen high-risk women at least annually and possibly under 35 years.

Clapperton(Julie A),Manke(Isaac A),Lowery(... Nat Struct Mol Biol 2004-07-15

Germline mutations in the BRCA1 tumor suppressor gene often result in a significant increase in susceptibility to breast...

Williams(R Scott),Lee(Megan S),Hau(D Duong... Nat Struct Mol Biol 2004-07-15

The BRCT repeats in BRCA1 are essential for its tumor suppressor activity and interact with phosphorylated protein targe...

Kirchhoff(Tomas),Kauff(Noah D),Mitra(Nandi... Clin Cancer Res 2004-11-10

...BRCA1 or BRCA2 compared with 28 (1.9%) controls. After adjusting for age, the presence of a BRCA1 or BRCA2 mutation was ...

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