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TP53 BRCA1 CRISPR single-cell cancer

Nippert(Irmgard),Schlegelberger(Brigitte), Community Genet 2004-11-23

In order to promote safe and effective testing for BRCA1 and BRCA2 mutations in clinical practice, a network of expert c...

Meng(Zhen Hang),Ben(Yong),Li(Zheng),Chew(K... Genes Chromosomes Cancer 2004-10-25

...BRCA1, BRCA2, and ATM revealed loss of heterozygosity (LOH) in tumor cells at 1 or more genes in 18 of 24 cases examined...

Butcher(Darci T),Mancini-DiNardo(Debora N)... Int J Cancer 2004-08-31

...BRCA1 promoter has been reported in a portion of sporadic breast tumours that correspond to a reduction in BRCA1 transcr...

Samouëlian(V),Maugard(C M),Jolicoeur(M),Be... Cancer Chemother Pharmacol 2004-12-14

...BRCA1, BRCA2, TGFbeta-RII, KRAS2, TP53, and CDKN2A. The observed responses to treatment are consistent with the current ...

Arlt(Martin F),Xu(Bo),Durkin(Sandra G),Cas... Mol Cell Biol 2004-08-16

...BRCA1 plays a key role. Furthermore, they suggest that mutations in BRCA1 or interacting proteins could lead to rearrang...

MMWR Morb Mortal Wkly Rep 2004-07-21

...BRCA1 and BRCA2 (BRCA1/2), are associated with predisposition for inherited breast and ovarian cancer and are identified...

Buchanan(Grant),Craft(Paul S),Yang(Miao),C... Prostate 2004-08-31

...BRCA1, and Zac1. Moreover, phenotypic differences of AR variants implicated in prostate cancer susceptibility and progre...

Lynch(Henry T),Shaw(Trudy G),Lynch(Jane F) Am J Med Genet C Semin Med ... 2004-09-22

...BRCA1 and BRCA2 germline mutations; the Li-Fraumeni (SBLA) syndrome due to the p53 mutation; and the familial atypical m...

Hodgson(Shirley V),Morrison(Patrick J),Irv... Am J Med Genet C Semin Med ... 2004-09-22

...BRCA1 and BRCA2. However, other less penetrant genes, including some autosomal recessive genes, are likely to be of etio...

Edwards(Stephen M),Eeles(Rosalind A) Am J Med Genet C Semin Med ... 2004-09-22

...BRCA1/2), familial colorectal cancer (HNPCC), retinoblastoma (RB1), and Wilms tumor (WT1). This review investigates the ...

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