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TP53 BRCA1 CRISPR single-cell cancer

Biglia(N),Defabiani(E),Ponzone(R),Mariani(... Endocr Relat Cancer 2004-10-12

...BRCA1/BRCA2) gene mutations, are associated with a fourfold increase in risk. A previous diagnosis of atypical ductal or...

Skibbens(Robert V) Genetics 2004-10-26

...BRCA1 to maintain genome integrity. Our findings document a novel role for Chl1p in sister-chromatid cohesion and provid...

Ohta(Tomohiko),Fukuda(Mamoru) Oncogene 2004-04-13

...BRCA1-BARD1; ErbB2/HER2/Neu and its ubiquitin ligase c-Cbl or CHIP; and the estrogen receptor and its downstream target ...

Hampl(J A),Hampl(M),Reiss(G),Koch(R),Saege... Anticancer Res 2004-05-21

...BRCA1 and p53 to predict the clinical course of sporadic breast cancer patients.,LOH analysis was performed by PCR ampli...

Bernard-Gallon(Dominique J),Dechelotte(Pie... Anticancer Res 2004-05-21

...BRCA1 or BRCA2. In contrast to normal breast epithelial cells, BRCA1 mRNA levels in tumors appeared to be down-regulated...

Zikán(M),Jancárková(N),Pohlreich(P),Matous... Cas Lek Cesk 2004-04-20

...BRCA1 and BRCA2 genes, which are responsible for almost three-quarters of those hereditary tumours.

Ganesan(Shridar),Silver(Daniel P),Drapkin(... Philos Trans R Soc Lond B B... 2004-05-05

...BRCA1 loss, the relevance of the BRCA1/Xi function to the tumour suppressor activity of BRCA1 remains unclear and needs ...

Barrois(M),Bièche(I),Mazoyer(S),Champème(M... Clin Genet 2004-09-27

...BRCA1 alterations is lower than that predicted by linkage analysis. Several large BRCA1 rearrangements have been identif...

Wang(Wensheng),Seki(Masayuki),Otsuki(Makot... Biochim Biophys Acta 2004-04-23

...BRCA1-associated genome surveillance complex (BASC), a supercomplex possibly involved in the recognition and repair of a...

Ouchi(Mutsuko),Fujiuchi(Nobuko),Sasai(Kaor... J Biol Chem 2004-06-15

...BRCA1 breast cancer tumor suppressor also localizes to the centrosome and that BRCA1 inactivation results in loss of the...

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