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BRCA1 and BRCA2: 1994 and beyond.

Narod(Steven A),Foulkes(William D) Nat Rev Cancer 2004-09-21

The discovery of the first gene associated with hereditary breast cancer, BRCA1, was anticipated to greatly increase our...

RNA helicase A interacts with nuclear factor kappaB p65 and functions as a tr...

Tetsuka(Toshifumi),Uranishi(Hiroaki),Sanda... Eur J Biochem 2004-10-18

...BRCA1, and links them to RNA Polymerase II holoenzyme complex. Using yeast two-hybrid screening, we have identified RHA ...

Characterization of a novel large deletion and single point mutations in the ...

Belogianni(Ioulia),Apessos(Angela),Mihalat... BMC Cancer 2004-11-12

...BRCA1 gene. Finally, MLPA revealed deletion of exon 20 of the BRCA1 gene in one family, a deletion that encompasses 3.2 ...

Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53...

Silverman(Joshua),Takai(Hiroyuki),Buonomo(... Genes Dev 2004-11-02

...BRCA1, Chk2, Nbs1, and Mre11. Rif1 inhibition resulted in radiosensitivity and a defect in the intra-S-phase checkpoint....

Attenuation of estrogen receptor alpha-mediated transcription through estroge...

Aiyar(Sarah E),Sun(Jian-long),Blair(Ashley... Genes Dev 2004-11-02

...BRCA1 (COBRA1), an integral subunit of the human negative elongation factor (NELF), directly binds to ERalpha and repres...

Tumor cell-specific BRCA1 and RASSF1A hypermethylation in serum, plasma, and ...

Ibanez de Caceres(Inmaculada),Battagli(Cri... Cancer Res 2004-11-04

...BRCA1 and RAS association domain family protein 1A tumor suppressor genes. Hypermethylation of one or both genes was fou...

[A paradox and three egnimas about the role of BRCA1 in breast and ovarian ca...

Feunteun(Jean) J Soc Biol 2004-12-09

...BRCA1 or BRCA2 genes (BReast CAncer 1/2). The BRCA1 protein is expressed ubiquitously and is likely to play a role in se...

Follicle stimulating hormone-induced growth promotion and gene expression pro...

Ji(Qing),Liu(Paul I),Chen(Peter K),Aoyama(... Int J Cancer 2004-11-26

...BRCA1, BS69) and the genes related to cell proliferation control. Pathway analysis found that FSH activates certain impo...

Mutant BRCA1 alleles transmission: different approaches and different biases.

de la Hoya(Miguel),Meijers-Heijboer(Hanne)... Int J Cancer 2004-12-07

Recently, a non-random transmission of BRCA1 mutant alleles to the off-spring of carriers has been suggested. If confirm...

[Are the hereditary forms of BRCA1 and BRCA2 breast cancer sensitive to estro...

Pujol(Pascal),This(Pascale),Noruzinia(Mehr... Bull Cancer 2004-12-21

...BRCA1 and BRCA2 related forms, could be in fact estrogen-sensitive. Interactions between BRCA1 gene expression and estro...

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